A Rare Case of Light Chain Amyloidosis of the Gastrointestinal Tract

Figure 3

Amyloid deposition in the stomach and liver. (a–d) Gastric mucosa with ulceration, fibrinopurulent exudate, regenerative changes, and hyalinization of lamina propria secondary to amyloid deposition (pink on hematoxylin and eosin (H&E), (a)), highlighted by a metachromatic reaction on crystal violet stain (magenta, (b)) and congophilia on Congo red stain (red, (c)) with apple-green birefringence on polarized light (d). (e–h). Core liver biopsy with diffuse hyalinized stroma (H&E, (e)) consistent with amyloid deposition demonstrated by crystal violet (f), Congo red stain (g), and apple-green birefringence on polarized light (h). Magnification: (a–d), 100x; (e–g), 200x; (h), 400x.

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