Case Report

Case Report of Synchronous Prostate, Hepatocellular, and Rectal Carcinomas and Review of the Literature

Table 1

The previously reported examples of synchronous triple primary malignancies including rectal, prostate, and hepatocellular cancers.

AuthorYearAge/genderMalignanciesTreatmentFollow-up

Okajima et al. [11]199475/MHCC-RCC-SqCC of the oral floorSimultaneous resection of all tumorsNot reported
Chang et al. [12]200374/MHCC-cholangiocarcinoma-GAWedge resection of RLL, LL, and subtotal gastrectomyUnder follow-up
Wang et al. [13]200862/MHCC-basaloid SqCC of the esophagus-SqCC of the gumCurative surgery for gum and esophagus cancers—no details described about HCC treatmentDied 5 months later of unrelated cause
Lee et al. [14]200869/MHCC-PC-papillary adenocarcinoma of the gallbladderSimultaneous wedge resection of the liver segment VII, pylorus-preserving pancreaticoduodenectomy, extended cholecystectomyNot reported
Lee et al. [15]201056/FRA-SqCC of cervix-PTCUterine conization-neoadjuvant chemoradiation therapy for the RA followed by palliative chemotherapy due to cancer peritonei12 months
Chong et al. [16]201080/MHCC-diffuse B-cell gastric lymphoma-GANo treatmentDied 30 days after diagnosis
Punit Tiwari et al. [17]201255/MPA-clear cell RCC-bladder TCCRadical nephroureterectomy followed 3 weeks later by total cystoprostatectomy2 years of follow-up
Guoliang and Dongsheng [18]201333/MHCC-CA-partial myxoadenocarcinoma, carcinoid of appendixRight colectomy-TACEDied of liver failure 8 months later
Yeh et al. [19]201379/MRA-cecal adenocarcinoma-right hepatic flexure adenocarcinomaSimultaneous low anterior resection and an extended right hemicolectomyNot reported
Ogawa et al. [20]201467/MA-penile SqCC-SCC of the bladderLaparoscopic radical cystectomy, urethrectomy, and partial penectomyNot reported
Cansu et al. [21]201462/MPA-bladder TCC-PTCRadical cystectomy followed by chemotherapy-total thyroidectomy 2 months after cystectomy combined with radioactive iodineUnder follow-up
Akiyama et al. [22]201573/MHCC-CA-SqCC of the esophagusSimultaneous sigmoidectomy and partial hepatectomy-esophagectomy after 49 days7 months
Yang et al. [23]201649/MRA-CA-gastric myxoadenocarcinomaSimultaneous laparoscopic distal gastrectomy, right hemicolectomy, and radical rectectomyNot reported
Long et al. [24]201962/MRA-PA-PTCChemoradiotherapy and hormonal therapy for RA and PA-clinical observation of thyroid carcinomaStable disease
Mira et al. [25]201971/MHCC, lung SCC, right tongue SCCRT for SCC of the lung-partial glossectomy-HCC treatment not reportedOne year

Abbreviations: RA: rectal adenocarcinoma; HCC: hepatocellular carcinoma; RCC: renal cell carcinoma; SqCC: squamous cell carcinoma; PTC: papillary thyroid carcinoma; GA: gastric adenocarcinoma; CA: colonic adenocarcinoma; TCC: transitional cell carcinoma; LA: lung adenocarcinoma; SCC: small-cell adenocarcinoma; RT: radiotherapy; LL: left lobectomy; RLL: right liver lobe.