Rare Anal Canal Cancer with Secondary Extramammary Paget’s Disease (Pagetoid Spread) Complicated by Squamous Cell Carcinoma of the Skin

Figure 6

Immunohistochemical analysis of the squamous cell carcinoma in the anal skin region. (a) Immunostaining for p63. The atypical squamous epithelium was positive for p63 in all layers. Pagetoid cells diffusely present in the epithelium were negative. (b) Immunostaining for CK5/6. The atypical squamous epithelium was positive for CK5/6 in all layers. Pagetoid cells diffusely present in the epithelium were negative.

(a)

(b)