Case Report

Splenic Artery Infarct Requiring Surgery: A Rare Complication of COVID-19 Infection

Table 2

Literature review of cases of COVID-19 with splenic infarcts.

AuthorSexAgeClinical presentationTreatmentOutcome

Atici and Akpinar [2]M45Splenic infarctLMWH (enoxaparin) followed by ASA and ticagrelorRecovered
Dennison et al. [3]M70Splenic infarct and bilateral rectus sheath hematomaLMWH (complication)Improvement
Dagistanli and Sonmez [4]F42Splenic infarct secondary to splenic vein thrombosis and splenic abscessLMWH (enoxaparin) percutaneous drainage and suctionImprovement
Redekar et al. [5]M55Multiple splenic infractsUFH LMWH plus acenocoumarolImprovement
Karki et al. [6]M32Splenic infarctionSupportive careSplenic rupture-ICU admission—outcome not reported
Moradi et al. [7]F59Splenic infarct and limb ischemia (foot)Heparin followed by rivaroxaban, ASA, and clopidogrelImprovement
Al-Mashdali et al. [8]M43Splenic and renal infarct (AKI)Heparin and warfarinImprovement
Tranca et al. [9]F30PostpartumLMWH plus antiplatelet agentsImprovement
Singh P. and Singh S. [10]M40Aortic thrombus and splenic infarctLMWH followed by rivaroxabanImprovement
Agha et al. [11]M60Splenic infarctionHeparin for 24 h IV infusion and then enoxaparin SC. Rivoroxaban on dischargeRecovered
Pistor et al. [12]M17Splenic artery thrombosis and acute strokeLMWH (enoxaparin) followed by aspirinImprovement
Prentice et al. [13]M50Splenic infarctUFH (heparin) followed by enoxaparinImprovement
Yildiz et al. [14]M68Splenic infracts plus pneumonic emboliLMWHImprovement
Castro et al. [16]M67Splenic infarctLMWH (enoxaparin) followed by rivaroxabanImprovement
Sztajnbok et al. [19]F60Splenic and aortic thrombosisLMWH (enoxaparin) followed by warfarinImprovement
Gold et al. [20]M59Extensive thrombosis of the thoracic and abdominal aorta, celiac trunk, hepatic artery, splenic artery and vein, spleen, and right kidney infarctionsLMWH (therapeutic dose)Deceased from sepsis 1 month after event
Gold et al. [20]M70Multiple brain infarctions, vascular occlusions of both lungs, spleen, and kidney infarctionsLMWH (therapeutic dose)Deceased 2 weeks after event
Gold et al. [20]M78Multiple pulmonary emboli with lung infarctions, spleen, and bilateral kidney infarctionsLMWH (therapeutic dose)Deceased 3 days after event
Mavraganis et al. [21]M64Simultaneous infracts at the splenic vein, artery, renal artery, and aortic thrombiLMWH plus acetylsalicylic acidRecovered
Vidali et al. [22]F70Splenic artery occlusion and splenoportal-mesenteric axis thrombosisLMWHNot reported
Roquetaillade et al. [23]Not mentionedAnticoagulation medical therapyNot reported
Hossri et al. [24]F29Splenic infarct and ischemic strokeHeparin in continuous infusionNot reported
Pessoa et al. [25]M67Splenic infarct and ischemic stroke plus pulmonaryNo informationNot reported
Pessoa et al. [25]F53Splenic infarctionNot reportedNot reported
Ghalib et al. [26]F67Splenic infarctUFH (heparin) followed by LMWHImprovement
Al Suwaidi et al. [27]F23Splenic infarctRivaroxabanImprovement
Norton and Sheikh [28]M30Occlusive thrombus in splenic arteryLMWH (tinzaparine) and warfarinImprovement
Mathew et al. [29]M34Splenic infarctLMWHImprovement
Javaid et al. [30]M44Celiac trunk thrombosis extended to spleenSupportively (not reported)Improvement
Ramanathan et al. [31]M54Bilateral renal and splenic infarctsApixabanRecovered
Mahmood et al. [32]F27Postpartum multiple splenic infarctsLMWH followed by rivaroxabanImprovement
Al-Ozaibi et al. [34]M57Splenic abscess with ruptureSplenectomyDied due to sepsis, MOF, and PE
Besutti et al. [35]M53Splenic infarction and left kidney infarctionLMWHRecovered
Besutti et al. [35]M72Massive splenic infarction and small bowel ischemiaSplenectomy and small bowel resectionRecovered
Imam and Hammond [36]F58Splenic vein, artery, and portal system thrombosisPercutaneous drainage of the abscess and splenectomyNot reported
Guven [37]M54Splenic and abdominal aortic thrombosisLMWH (enoxaparin)Improvement (complete resolution of thrombus)
Jahromi et al. [38]M76Renal, splenic, and myocardial infarctionHeparin followed by oral anticoagulantsImprovement
Do et al. [39]M66Splenic infarct and infrarenal thrombusEnoxaparin followed by heparin and enoxaparinImprovement
Imoto et al. [40]M64Multiple cerebral infracts, bilateral renal infracts, splenic infarctionLMWHDied on hospitalization
Cetiner et al. [41]M71Splenic infarct and strokeLMWH (enoxaparin)Improvement
Fernandes et al. [42]M44Splenic and arterial thrombiLMWH (enoxaparin)Improvement
Arslan [43]F42Splenic venous and arterial thrombosis and celiac artery thrombiHeparin followed by enoxaparin and ASAImprovement
Rigual et al. [44]M53Splenic, cerebral, and bilateral renal infarctsLMWH (enoxaparin) followed by acetylsalicylicImprovement