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Case Reports in Transplantation
Volume 2013, Article ID 969186, 5 pages
http://dx.doi.org/10.1155/2013/969186
Case Report

Severe Necrotizing Adenovirus Tubulointerstitial Nephritis in a Kidney Transplant Recipient

1Division of Transplantation and Department of Pathology, Royal Oak, MI 48703, USA
2Oakland University William Beaumont School of Medicine, William Beaumont Hospital, Royal Oak, MI 48703, USA
3Beaumont Health System, Royal Oak, MI 48703, USA

Received 29 May 2013; Accepted 8 July 2013

Academic Editors: P. A. Andrews, A. Beiras-Fernandez, and I. Engelmann

Copyright © 2013 Ravi Parasuraman et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. M. G. Ison, “Adenovirus infections in transplant recipients,” Clinical Infectious Diseases, vol. 43, no. 3, pp. 331–339, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. A. Humar, D. Kumar, T. Mazzulli et al., “A surveillance study of adenovirus infection in adult solid organ transplant recipients,” American Journal of Transplantation, vol. 5, no. 10, pp. 2555–2559, 2005. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Ito, N. Hirabayashi, Y. Uno, A. Nakayama, and J. Asai, “Necrotizing tubulointerstitial nephritis associated with adenovirus infection,” Human Pathology, vol. 22, no. 12, pp. 1225–1231, 1991. View at Publisher · View at Google Scholar · View at Scopus
  4. J. Kapelushnik, A. Verstandig, R. Or et al., “Hydronephrosis in children after bone marrow transplantation: case reports,” Bone Marrow Transplantation, vol. 17, no. 5, pp. 873–875, 1996. View at Google Scholar · View at Scopus
  5. A. K. H. Lim, S. Parsons, and F. Ierino, “Adenovirus tubulointerstitial nephritis presenting as a renal allograft space occupying lesion,” American Journal of Transplantation, vol. 5, no. 8, pp. 2062–2066, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. L. M. Kolankiewicz, J. Pullman, M. Raffeld, J. B. Kopp, and D. Glicklich, “Adenovirus nephritis and obstructive uropathy in a renal transplant recipient: case report and literature review,” NDT Plus, vol. 3, no. 4, pp. 388–392, 2010. View at Publisher · View at Google Scholar · View at Scopus
  7. L. Storsley and I. W. Gibson, “Adenovirus interstitial nephritis and rejection in an allograft,” Journal of the American Society of Nephrology, vol. 22, no. 8, pp. 1423–1427, 2011. View at Publisher · View at Google Scholar · View at Scopus
  8. S. P. Watcharananan, R. Avery, A. Ingsathit et al., “Adenovirus disease after kidney transplantation: course of infection and outcome in relation to blood viral load and immune recovery,” American Journal of Transplantation, vol. 11, no. 6, pp. 1308–1314, 2011. View at Publisher · View at Google Scholar · View at Scopus
  9. O. Ruuskanen, O. Meurman, and G. Akusjarvi, “Adenoviruses,” in Clinical Virology, D. D. Richmann, R. J. Whitley, and F. G. Hayden, Eds., pp. 515–535, ASM Press, Washington, DC, USA, 2002. View at Google Scholar
  10. M. Echavarria, “Adenoviruses in immunocompromised hosts,” Clinical Microbiology Reviews, vol. 21, no. 4, pp. 704–715, 2008. View at Google Scholar
  11. B. Kampmann, D. Cubitt, T. Walls et al., “Improved outcome for children with disseminated adenoviral infection following allogeneic stem cell transplantation,” British Journal of Haematology, vol. 130, no. 4, pp. 595–603, 2005. View at Publisher · View at Google Scholar · View at Scopus
  12. R. H. Rubin, S. A. Kemmerly, D. Conti et al., “Prevention of primary cytomegalovirus disease in organ transplant recipients with oral ganciclovir or oral acyclovir prophylaxis,” Transplant Infectious Disease, vol. 2, no. 3, pp. 112–117, 2000. View at Publisher · View at Google Scholar · View at Scopus
  13. R. R. Razonable and A. J. Eid, “Viral infections in transplant recipients,” Minerva Medica, vol. 100, no. 6, pp. 479–501, 2009. View at Google Scholar · View at Scopus
  14. T. Kojaoghlanian, P. Flomenberg, and M. S. Horwitz, “The impact of adenovirus infection on the immunocompromised host,” Reviews in Medical Virology, vol. 13, no. 3, pp. 155–171, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. L. R. Krilov, “Adenovirus infections in the immunocompromised host,” Pediatric Infectious Disease Journal, vol. 24, no. 6, pp. 555–556, 2005. View at Publisher · View at Google Scholar · View at Scopus
  16. N. Singh-Naz, M. Brown, and M. Ganeshananthan, “Nosocomial adenovirus infection: molecular epidemiology of an outbreak,” Pediatric Infectious Disease Journal, vol. 12, no. 11, pp. 922–925, 1993. View at Google Scholar · View at Scopus
  17. V. Venard, A.-S. Carret, D. Corsaro, P. Bordigoni, and A. Le Faou, “Genotyping of adenoviruses isolated in an outbreak in a bone marrow transplant unit shows that diverse strains are involved,” Journal of Hospital Infection, vol. 44, no. 1, pp. 71–74, 2000. View at Publisher · View at Google Scholar · View at Scopus
  18. J. C. Hierholzer, “Adenoviruses in the immunocompromised host,” Clinical Microbiology Reviews, vol. 5, no. 3, pp. 262–274, 1992. View at Google Scholar · View at Scopus
  19. T. Umekawa and T. Kurita, “Acute hemorrhagic cystitis by adenovirus type 11 with and without type 37 after kidney transplantation,” Urologia Internationalis, vol. 56, no. 2, pp. 114–116, 1996. View at Google Scholar · View at Scopus
  20. M. Asim, A. Chong-Lopez, and V. Nickeleit, “Adenovirus infection of a renal allograft,” American Journal of Kidney Diseases, vol. 41, no. 3, pp. 696–701, 2003. View at Publisher · View at Google Scholar · View at Scopus
  21. A. Gaspert, B. Lüthi, N. J. Mueller et al., “Subacute allograft failure with dysuria and hematuria in a kidney transplant recipient,” American Journal of Kidney Diseases, vol. 54, no. 1, pp. 154–158, 2009. View at Publisher · View at Google Scholar · View at Scopus
  22. P. Randhawa, “Adnenovirus nephritis: a pathologic perspective,” eAJKD the Official Blog of AJKD. In press.
  23. A. C. Lankester, M. J. D. Van Tol, E. C. J. Claas, J. M. Vossen, and A. C. M. Kroes, “Quantification of adenovirus DNA in plasma for management of infection in stem cell graft recipients,” Clinical Infectious Diseases, vol. 34, no. 6, pp. 864–867, 2002. View at Publisher · View at Google Scholar · View at Scopus
  24. M. Keddis, N. Leung, S. Herrmann, Z. El-Zoghby, and S. Sethi, “Adenovirus-induced interstitial nephritis following umbilical cord blood transplant for chronic lymphocytic leukemia,” American Journal of Kidney Diseases, vol. 59, no. 6, pp. 886–890, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. P. Ljungman, P. Ribaud, M. Eyrich et al., “Cidofovir for adenovirus infections after allogeneic hematopoietic stem cell transplantation: a survey by the Infectious Diseases Working Party of the European Group for Blood and Marrow Transplantation,” Bone Marrow Transplantation, vol. 31, no. 6, pp. 481–486, 2003. View at Publisher · View at Google Scholar · View at Scopus
  26. K. Nagafuji, K. Aoki, H. Henzan et al., “Cidofovir for treating adenoviral hemorrhagic cystitis in hematopoietic stem cell transplant recipients,” Bone Marrow Transplantation, vol. 34, no. 10, pp. 909–914, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. D. F. Florescu, S. A. Pergam, M. N. Neely et al., “Safety and efficacy of CMX001 as salvage therapy for severe adenovirus infections in immunocompromised patients,” Biology of Blood and Marrow Transplantation, vol. 18, no. 5, pp. 731–738, 2012. View at Publisher · View at Google Scholar · View at Scopus