Table of Contents Author Guidelines Submit a Manuscript
Case Reports in Transplantation
Volume 2013, Article ID 978481, 5 pages
http://dx.doi.org/10.1155/2013/978481
Case Report

De Novo Fibrillary Glomerulonephritis (FGN) in a Renal Transplant with Chronic Hepatitis C

1Department of Medicine, Thomas Jefferson University, 2228 South Broad Street, Philadelphia, PA 19145, USA
2Division of Nephrology, Thomas Jefferson University, Philadelphia, PA 19107, USA
3Department of Pathology, Thomas Jefferson University, Philadelphia, PA 19107, USA

Received 8 May 2013; Accepted 5 June 2013

Academic Editors: P. A. Andrews, M. L. Coppage, R. L. Heilman, F. Keller, and S. Pinney

Copyright © 2013 Edward J. Filippone et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. D'Amico, “Renal involvement in hepatitis C infection: cryoglobulinemic glomerulonephritis,” Kidney International, vol. 54, no. 2, pp. 650–671, 1998. View at Publisher · View at Google Scholar · View at Scopus
  2. B. Domínguez-Gil and J. M. Morales, “Transplantation in the patient with hepatitis C,” Transplant International, vol. 22, no. 12, pp. 1117–1131, 2009. View at Publisher · View at Google Scholar · View at Scopus
  3. O. Trejo, M. Ramos-Casals, M. García-Carrasco et al., “Cryoglobulinemia: study of etiologic factors and clinical and immunologic features in 443 patients from a single center,” Medicine, vol. 80, no. 4, pp. 252–262, 2001. View at Publisher · View at Google Scholar · View at Scopus
  4. D. Roccatello, A. Fornasieri, O. Giachino et al., “Multicenter study on hepatitis C virus-related cryoglobulinemic glomerulonephritis,” The American Journal of Kidney Diseases, vol. 49, no. 1, pp. 69–82, 2007. View at Publisher · View at Google Scholar · View at Scopus
  5. R. J. Johnson, D. R. Gretch, H. Yamabe et al., “Membranoproliferative glomerulonephritis associated with hepatitis C virus infection,” The New England Journal of Medicine, vol. 328, no. 7, pp. 465–470, 1993. View at Publisher · View at Google Scholar · View at Scopus
  6. R. J. Johnson, D. R. Gretch, W. G. Couser et al., “Hepatitis C virus-associated glomerulonephritis. Effect of α-interferon therapy,” Kidney International, vol. 46, no. 6, pp. 1700–1704, 1994. View at Google Scholar · View at Scopus
  7. H. Yamabe, R. J. Johnson, D. R. Gretch et al., “Hepatitis C virus infection and membranoproliferative glomerulonephritis in Japan,” Journal of the American Society of Nephrology, vol. 6, no. 2, pp. 220–223, 1995. View at Google Scholar · View at Scopus
  8. F. G. Cosio, Z. Roche, A. Agarwal, M. E. Falkenhain, D. D. Sedmak, and R. M. Ferguson, “Prevalence of hepatitis c in patients with idiopathic glomerulopathies in native and transplant kidneys,” The American Journal of Kidney Diseases, vol. 28, no. 5, pp. 752–758, 1996. View at Google Scholar · View at Scopus
  9. C. Stehman-Breen, C. E. Alpers, W. G. Couser, R. Willson, and R. J. Johnson, “Hepatitis C virus associated membranous glomerulonephritis,” Clinical Nephrology, vol. 44, no. 3, pp. 141–147, 1995. View at Google Scholar · View at Scopus
  10. E. Coroneos, L. Truong, and J. Olivero, “Renal biopsy case: fibrillary glomerulonephritis associated with hepatitis C viral infection,” The American Journal of Kidney Diseases, vol. 29, no. 1, pp. 132–135, 1997. View at Google Scholar · View at Scopus
  11. G. Guerra, G. Narayan, H. G. Rennke, and B. L. Jaber, “Crescentic fibrillary glomerulonephritis associated with hepatitis C viral infection,” Clinical Nephrology, vol. 60, no. 5, pp. 364–368, 2003. View at Google Scholar · View at Scopus
  12. S. Ray, K. Rouse, A. Appis, R. Novak, and N. A. Haller, “Fibrillary glomerulonephritis with hepatitis C viral infection and hypocomplementemia,” Renal Failure, vol. 30, no. 7, pp. 759–762, 2008. View at Publisher · View at Google Scholar · View at Scopus
  13. G. S. Markowitz, J.-T. Cheng, R. B. Colvin, W. M. Trebbin, and V. D. D'Agati, “Hepatitis C viral infection is associated with fibrillary glomerulonephritis and immunotactoid glomerulopathy,” Journal of the American Society of Nephrology, vol. 9, no. 12, pp. 2244–2252, 1998. View at Google Scholar · View at Scopus
  14. J. L. Rosenstock, G. S. Markowitz, A. M. Valeri, G. Sacchi, G. B. Apple, and V. D. D'Agati, “Fibrillary and immunotactoid glomerulonephritis: distinct entities with different clinical and pathologic features,” Kidney International, vol. 63, no. 4, pp. 1450–1461, 2003. View at Publisher · View at Google Scholar · View at Scopus
  15. S. Nasr, A. M. Valeri, L. D. Cornell et al., “Fibrillary glomerulonephritis: a report of 66 cases from a single institution,” Clinical Journal of the American Society of Nephrology, vol. 6, no. 4, pp. 775–784, 2011. View at Publisher · View at Google Scholar · View at Scopus
  16. A. A. Sabry, M. A. Sobh, W. L. Irving et al., “A comprehensive study of the association between hepatitis C virus and glomerulopathy,” Nephrology Dialysis Transplantation, vol. 17, no. 2, pp. 239–245, 2002. View at Google Scholar · View at Scopus
  17. D. Sansonno, L. Gesualdo, C. Manno, F. P. Schena, and F. Dammacco, “Hepatitis C virus-related proteins in kidney tissue from hepatitis C virus-infected patients with cryoglobulinemic membranoproliferative glomerulonephritis,” Hepatology, vol. 25, no. 5, pp. 1237–1244, 1997. View at Google Scholar · View at Scopus
  18. D. Sansonno, G. Lauletta, M. Montrone, G. Grandaliano, F. P. Schena, and F. Dammacco, “Hepatitis C virus RNA and core protein in kidney glomerular and tubular structures isolated with laser capture microdissection,” Clinical and Experimental Immunology, vol. 140, no. 3, pp. 498–506, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. K. Okada, Y. Takishita, H. Shimomura et al., “Detection of hepatitis C virus core protein in the glomeruli of patients with membranous glomerulonephritis,” Clinical Nephrology, vol. 45, no. 2, pp. 71–76, 1996. View at Google Scholar · View at Scopus
  20. Y. Cao, Y. Zhang, S. Wang, and W. Zou, “Detection of the hepatitis C virus antigen in kidney tissue from infected patients with various glomerulonephritis,” Nephrology Dialysis Transplantation, vol. 24, no. 9, pp. 2745–2751, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. K. Kasuno, T. Ono, A. Matsumori et al., “Hepatitis C virus-associated tubulointerstitial injury,” The American Journal of Kidney Diseases, vol. 41, no. 4, pp. 767–775, 2003. View at Google Scholar · View at Scopus
  22. B. J. G. Pereira, S. N. Natov, B. A. Bouthot et al., “Effect of hepatitis C infection and renal transplantation on survival in end-stage renal disease,” Kidney International, vol. 53, no. 5, pp. 1374–1381, 1998. View at Publisher · View at Google Scholar · View at Scopus
  23. D. Hestin, F. Guillemin, N. Castin, A. Le Faou, J. Champigneulles, and M. Kessler, “Pretransplant hepatitis C virus infection: a predictor of proteinuria after renal transplantation,” Transplantation, vol. 65, no. 5, pp. 741–744, 1998. View at Publisher · View at Google Scholar · View at Scopus
  24. D. Roth, R. Cirocco, K. Zucker et al., “De novo membranoproliferative glomerulonephritis in hepatitis C virus- infected renal allograft recipients,” Transplantation, vol. 59, no. 12, pp. 1676–1682, 1995. View at Google Scholar · View at Scopus
  25. J. M. Cruzado, S. Gil-Vernet, G. Ercilla et al., “Hepatitis C virus-associated membranoproliferative glomerulonephritis in renal allografts,” Journal of the American Society of Nephrology, vol. 7, no. 11, pp. 2469–2475, 1996. View at Google Scholar · View at Scopus
  26. J. M. Cruzado, M. Carrera, J. Torras, and J. M. Grinyó, “Hepatitis C virus infection and de novo glomerular lesions in renal allografts,” The American Journal of Transplantation, vol. 1, no. 2, pp. 171–178, 2001. View at Google Scholar · View at Scopus
  27. B. H. Özdemir, F. N. Özdemir, S. Sezer, T. Çolak, and M. Haberal, “De novo glomerulonephritis in renal allografts with hepatitis C virus infection,” Transplantation Proceedings, vol. 38, no. 2, pp. 492–495, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. J. M. Morales, J. Pascual-Capdevila, J. M. Campistol et al., “Membranous glomerulonephritis associated with hepatitis C virus infection in renal transplant patients,” Transplantation, vol. 63, no. 11, pp. 1634–1639, 1997. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Baid, M. Pascual, W. W. Williams Jr. et al., “Renal thrombotic microangiopathy associated with anticardiolipin antibodies in hepatitis C-positive renal allograft recipients,” Journal of the American Society of Nephrology, vol. 10, no. 1, pp. 146–153, 1999. View at Google Scholar · View at Scopus
  30. S. Baid-Agrawal, A. B. Farris, M. Pascual et al., “Overlapping pathways to transplant glomerulopathy: chronic humoral rejection, hepatitis C infection, and thrombotic microangiopathy,” Kidney International, vol. 80, no. 8, pp. 879–885, 2011. View at Publisher · View at Google Scholar · View at Scopus
  31. D. N. Howell, X. Gu, and G. A. Herrera, “Organized deposits in the kidney and look-alikes,” Ultrastructural Pathology, vol. 27, no. 5, pp. 295–312, 2003. View at Google Scholar · View at Scopus
  32. G. A. Herrera and E. A. Turat-Herrera, “Renal diseases with organized deposits,” Archives of Pathology and Laboratory Medicine, vol. 134, pp. 512–531, 2010. View at Google Scholar
  33. D. Cordonnier, H. Martin, P. Groslambert, C. Micouin, F. Chenais, and P. Stoebner, “Mixed IgG IgM cryoglobulinemia with glomerulonephritis. Immunochemical, fluorescent and ultrastructural study of kidney and in vitro cryoprecipitate,” The American Journal of Medicine, vol. 59, no. 6, pp. 867–872, 1975. View at Google Scholar · View at Scopus
  34. P. H. Pronovost, H. R. Brady, M. E. Gunning, O. Espinoza, and H. G. Rennke, “Clinical features, predictors of disease progression and results of renal transplantation in fibrillary/immunotactoid glomerulopathy,” Nephrology Dialysis Transplantation, vol. 11, no. 5, pp. 837–842, 1996. View at Google Scholar · View at Scopus
  35. S. M. Korbert, M. M. Schwartz, B. F. Rosenberg, R. K. Sibley, and E. J. Lewis, “Immunotactoid glomerulopathy,” Medicine, vol. 64, no. 4, pp. 228–243, 1985. View at Google Scholar · View at Scopus
  36. K. V. Rao, G. P. Hafner, G. S. Crary, W. R. Anderson, and J. T. Crosson, “De novo immunotactoid glomerulopathy of the renal allograft: possible association with cytomegalovirus infection,” The American Journal of Kidney Diseases, vol. 24, no. 1, pp. 97–103, 1994. View at Google Scholar · View at Scopus
  37. J. Isaac, G. A. Herrara, and F. S. Shihab, “De novo fibrillary glomerulopathy in the renal allograft of a patient with systemic lupus erythematosus,” Nephron, vol. 87, no. 4, pp. 365–368, 2001. View at Publisher · View at Google Scholar · View at Scopus
  38. G. Geri, B. Terrier, O. Semoun et al., “Surrogate markers of B cell non-Hodgkin's lymphoma in patients with hepatitis C virus-related cryoglobulinaemia vasculitis,” Annals of the Rheumatic Diseases, vol. 69, no. 12, pp. 2177–2180, 2010. View at Publisher · View at Google Scholar · View at Scopus
  39. P. G. Czarnecki, D. J. Lager, N. Leung, A. Dispenzieri, F. G. Cosio, and F. C. Fervenza, “Long-term outcome of kidney transplantation in patients with fibrillary glomerulonephritis or monoclonal gammopathy with fibrillary deposits,” Kidney International, vol. 75, no. 4, pp. 420–427, 2009. View at Publisher · View at Google Scholar · View at Scopus