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Case Reports in Transplantation
Volume 2014, Article ID 160407, 3 pages
http://dx.doi.org/10.1155/2014/160407
Case Report

Leukocytoclastic Vasculitis as a Complication of Recombinant Granulocyte Colony-Stimulating Factor Therapy in a Heart Transplant Patient

1U.O Medicina Interna, Policlinico di Monza, Via C. Amati 111, 20900 Monza, Italy
2Division of Cardiac Surgery, University of Pavia School of Medicine, Foundation “I.R.C.C.S. San Matteo” Hospital, Pavia, Italy
3Anatomic Pathology, Foundation IRCCS Policlinico San Matteo, University of Pavia, Italy

Received 18 September 2013; Accepted 16 December 2013; Published 30 January 2014

Academic Editors: F. Meloni and M. Sadeghi

Copyright © 2014 Giovanbattista Ippoliti et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. S. J. Jessop, “Cutaneous leucocytoclastic vasculitis: a clinical and aetiological study,” British Journal of Rheumatology, vol. 34, no. 10, pp. 942–945, 1995. View at Google Scholar · View at Scopus
  2. M. S. Aapro, J. Bohlius, D. A. Cameron et al., “2010 update of EORTC guidelines for the use of granulocyte-colony stimulating factor to reduce the incidence of chemotherapy-induced febrile neutropenia in adult patients with lymphoproliferative disorders and solid tumours,” European Journal of Cancer, vol. 47, no. 1, pp. 8–32, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. A. D'Souza, I. Jaiyesimi, L. Trainor, and P. Venuturumili, “Granulocyte colony-stimulating factor administration: adverse events,” Transfusion Medicine Reviews, vol. 22, no. 4, pp. 280–290, 2008. View at Publisher · View at Google Scholar · View at Scopus
  4. G. Morstyn, L. Campbell, L. M. Souza et al., “Effect of granulocyte colony stimulating factor on neutropenia induced by cytotoxic chemotherapy,” The Lancet, vol. 1, no. 8587, pp. 667–672, 1988. View at Google Scholar · View at Scopus
  5. H. J. Ross, L. A. Moy, R. Kaplan, and R. A. Figlin, “Bullous pyoderma gangrenosum after granulocyte colony-stimulating factor treatment,” Cancer, vol. 68, pp. 441–443, 1991. View at Google Scholar
  6. J. M. L. White, G. J. Mufti, J. R. Salisbury, and A. W. P. Du Vivier, “Cutaneous manifestations of granulocyte colony-stimulating factor,” Clinical and Experimental Dermatology, vol. 31, no. 2, pp. 206–207, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. K. K. Jain, “Cutaneous vasculitis associated with granulocyte colony-stimulating factor,” Journal of the American Academy of Dermatology, vol. 31, no. 2, pp. 213–215, 1994. View at Google Scholar · View at Scopus
  8. D. C. Dale, T. E. Cottle, C. J. Fier et al., “Severe chronic neutropenia: treatment and follow-up of patients in the Severe Chronic Neutropenia International Registry,” American Journal of Hematology, vol. 72, no. 2, pp. 82–93, 2003. View at Publisher · View at Google Scholar · View at Scopus
  9. T. Shiohara, Y. Sagawa, and M. Nagashima, “Systemic release of interferon-γ in drug-induced cutaneous vasculitis,” The Lancet, vol. 339, no. 8798, p. 933, 1992. View at Publisher · View at Google Scholar · View at Scopus
  10. J. Elsner, J. Roesler, A. Emmendorffer, C. Zeidler, M.-L. Lohmann-Matthes, and K. Welte, “Altered function and surface marker expression of neutrophils induced by rhG-CSF treatment in severe congenital neutropenia,” European Journal of Haematology, vol. 48, no. 1, pp. 10–19, 1992. View at Google Scholar · View at Scopus
  11. H. Zoellner, E. L. Filonzi, H. R. Stanton, J. E. Layton, and J. A. Hamilton, “Human arterial smooth muscle cells synthesize granulocyte colony-stimulating factor in response to interleukin-1α and tumor necrosis factor- α,” Blood, vol. 80, no. 11, pp. 2805–2810, 1992. View at Google Scholar · View at Scopus
  12. K. Spiekermann, A. Emmendoerffer, J. Elsner et al., “Altered surface marker expression and function of G-CSF-induced neutrophils from test subjects and patients under chemotherapy,” British Journal of Haematology, vol. 87, no. 1, pp. 31–38, 1994. View at Google Scholar · View at Scopus
  13. T. E. Cottle, C. J. Fier, J. Donadieu, and S. E. Kinsey, “Risk and benefit of treatment of severe chronic neutropenia with granulocyte colony-stimulating factor,” Seminars in Hematology, vol. 39, no. 2, pp. 134–140, 2002. View at Google Scholar · View at Scopus
  14. S. Schmaldienst, G. Bekesi, R. Deicher, M. Franz, W. H. Hörl, and E. Pohanka, “Recombinant human granulocyte colony-stimulating factor after kidney transplantation: a retrospective analysis to evaluate the benefit or risk of immunostimulation,” Transplantation, vol. 69, no. 4, pp. 527–531, 2000. View at Google Scholar · View at Scopus
  15. C. Minguez, A. Mazuecos, M. Ceballos, F. Tejuca, and M. Rivero, “Worsening of renal function in a renal transplant patient treated with granulocyte colony-stimulating factor,” Nephrology Dialysis Transplantation, vol. 10, no. 11, pp. 2166–2167, 1995. View at Google Scholar · View at Scopus
  16. V. R. Peddi, S. Hariharan, T. J. Schroeder, and M. R. First, “Role of granulocyte colony stimulating factor (G-CSF) in reversing neutropenia in renal allograft recipients,” Clinical Transplantation, vol. 10, no. 1 I, pp. 20–23, 1996. View at Google Scholar · View at Scopus
  17. F. P. Hurst, P. Belur, R. Nee et al., “Poor outcomes associated with neutropenia after kidney transplantation: analysis of united states renal data system,” Transplantation, vol. 92, no. 1, pp. 36–40, 2011. View at Publisher · View at Google Scholar · View at Scopus