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Case Reports in Transplantation
Volume 2016, Article ID 7137584, 4 pages
http://dx.doi.org/10.1155/2016/7137584
Case Report

Successful Treatment of Focal Segmental Glomerulosclerosis after Kidney Transplantation with Plasma Exchange and Abatacept in a Patient with Juvenile Rheumatoid Arthritis

1Department of Nephrology and Dialysis, Academic Teaching Hospital Feldkirch, 6800 Feldkirch, Austria
2Vorarlberg Institute for Vascular Investigation and Treatment, Academic Teaching Hospital Feldkirch, 6800 Feldkirch, Austria
3Clinical Pathology and Cytodiagnostics, 6060 Hall in Tirol, Austria

Received 22 January 2016; Revised 1 March 2016; Accepted 3 March 2016

Academic Editor: Ryszard Grenda

Copyright © 2016 Hannelore Sprenger-Mähr et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. M. Briganti, G. R. Russ, J. J. McNeil, R. C. Atkins, and S. J. Chadban, “Risk of renal allograft loss from recurrent glomerulonephritis,” The New England Journal of Medicine, vol. 347, no. 2, pp. 103–109, 2002. View at Publisher · View at Google Scholar · View at Scopus
  2. P. Cravedi, J. B. Kopp, and G. Remuzzi, “Recent progress in the pathophysiology and treatment of FSGS recurrence,” American Journal of Transplantation, vol. 13, no. 2, pp. 266–274, 2013. View at Publisher · View at Google Scholar · View at Scopus
  3. C. Wei, S. El Hindi, J. Li et al., “Circulating urokinase receptor as a cause of focal segmental glomerulosclerosis,” Nature Medicine, vol. 17, no. 8, pp. 952–960, 2011. View at Publisher · View at Google Scholar · View at Scopus
  4. V. J. Savin, M. Sharma, J. Zhou et al., “Renal and hematological effects of CLCF-1, a b-cell-stimulating cytokine of the il-6 family,” Journal of Immunology Research, vol. 2015, Article ID 714964, 11 pages, 2015. View at Publisher · View at Google Scholar · View at Scopus
  5. M. Delville, T. K. Sigdel, C. Wei et al., “A circulating antibody panel for pretransplant prediction of FSGS recurrence after kidney transplantation,” Science Translational Medicine, vol. 6, no. 256, Article ID 256ra136, 2014. View at Publisher · View at Google Scholar · View at Scopus
  6. J. Reiser, G. von Gersdorff, M. Loos et al., “Induction of B7-1 in podocytes is associated with nephrotic syndrome,” The Journal of Clinical Investigation, vol. 113, no. 10, pp. 1390–1397, 2004. View at Publisher · View at Google Scholar · View at Scopus
  7. C. Ponticelli, “Recurrence of focal segmental glomerular sclerosis (FSGS) after renal transplantation,” Nephrology Dialysis Transplantation, vol. 25, no. 1, pp. 25–31, 2010. View at Publisher · View at Google Scholar · View at Scopus
  8. C. E. Araya and V. R. Dharnidharka, “The factors that may predict response to rituximab therapy in recurrent focal segmental glomerulosclerosis: a systematic review,” Journal of Transplantation, vol. 2011, Article ID 374213, 7 pages, 2011. View at Publisher · View at Google Scholar
  9. C.-C. Yu, A. Fornoni, A. Weins et al., “Abatacept in B7-1-positive proteinuric kidney disease,” The New England Journal of Medicine, vol. 369, no. 25, pp. 2416–2423, 2013. View at Publisher · View at Google Scholar · View at Scopus
  10. B. Haraldsson, “A new era of podocyte-targeted therapy for proteinuric kidney disease,” The New England Journal of Medicine, vol. 369, no. 25, pp. 2453–2454, 2013. View at Publisher · View at Google Scholar · View at Scopus
  11. P. S. Linsley, W. Brady, M. Urnes, L. S. Grosmaire, N. K. Damle, and J. A. Ledbetter, “CTLA-4 is a second receptor for the B cell activation antigen B7,” The Journal of Experimental Medicine, vol. 174, no. 3, pp. 561–569, 1991. View at Publisher · View at Google Scholar · View at Scopus
  12. M. C. Genovese, J.-C. Becker, M. Schiff et al., “Abatacept for rheumatoid arthritis refractory to tumor necrosis factor α inhibition,” The New England Journal of Medicine, vol. 353, no. 11, pp. 1114–1123, 2005. View at Publisher · View at Google Scholar · View at Scopus
  13. F. Vincenti, B. Charpentier, Y. Vanrenterghem et al., “A phase III study of belatacept-based immunosuppression regimens versus cyclosporine in renal transplant recipients (BENEFIT Study),” American Journal of Transplantation, vol. 10, no. 3, pp. 535–546, 2010. View at Publisher · View at Google Scholar · View at Scopus
  14. R. J. Greenwald, G. J. Freeman, and A. H. Sharpe, “The B7 family revisited,” Annual Review of Immunology, vol. 23, pp. 515–548, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. N. Alachkar, N. Carter-Monroe, and J. Reiser, “Abatacept in B7-1-positive proteinuric kidney disease,” The New England Journal of Medicine, vol. 370, no. 13, pp. 1263–1264, 2014. View at Publisher · View at Google Scholar · View at Scopus
  16. E. H. Garin, J. Reiser, G. Cara-Fuentes et al., “Case series: CTLA4-IgG1 therapy in minimal change disease and focal segmental glomerulosclerosis,” Pediatric Nephrology, vol. 30, no. 3, pp. 469–477, 2014. View at Publisher · View at Google Scholar · View at Scopus
  17. M. Delville, E. Baye, A. Durrbach et al., “B7-1 blockade does not improve post-transplant nephrotic syndrome caused by recurrent FSGS,” Journal of the American Society of Nephrology, 2015. View at Publisher · View at Google Scholar
  18. R. Novelli, E. Gagliardini, B. Ruggiero, A. Benigni, and G. Remuzzi, “Any value of podocyte B7-1 as a biomarker in human MCD and FSGS?” American Journal of Physiology-Renal Physiology, vol. 310, no. 5, pp. F335–F341, 2016. View at Publisher · View at Google Scholar
  19. N. Ruperto, D. J. Lovell, P. Quartier et al., “Long-term safety and efficacy of abatacept in children with juvenile idiopathic arthritis,” Arthritis and Rheumatism, vol. 62, no. 6, pp. 1792–1802, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. N. Bassil, L. Rostaing, C. Mengelle et al., “Prospective monitoring of cytomegalovirus, Epstein-Barr virus, BK virus, and JC virus infections on belatacept therapy after a kidney transplant,” Experimental and Clinical Transplantation, vol. 12, no. 3, pp. 212–219, 2014. View at Publisher · View at Google Scholar · View at Scopus