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Case Reports in Transplantation
Volume 2017 (2017), Article ID 6401086, 5 pages
Case Report

Posttransplant Lymphoproliferative Disease Presenting as an Extracranial Mass

Department of Medicine, Section of Infectious Diseases, Baylor College of Medicine, Houston, TX, USA

Correspondence should be addressed to Reuben J. Arasaratnam

Received 9 May 2017; Revised 7 August 2017; Accepted 30 August 2017; Published 11 October 2017

Academic Editor: Ryszard Grenda

Copyright © 2017 Reuben J. Arasaratnam and Alejandro Restrepo. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Posttransplant lymphoproliferative disease is a serious complication following stem cell and solid organ transplantation. Early recognition of the disease is important in facilitating timely therapy and improving long-term outcomes. We report a renal transplant recipient presenting with an extracranial frontoparietal soft tissue mass that was subsequently diagnosed as a B-cell lymphoma. The patient was treated successfully with immunosuppression reduction, anti-CD20 monoclonal antibody therapy, and cytotoxic chemotherapy. Our case highlights the importance of recognizing soft tissue masses in the head and neck as a potential clinical manifestation of PTLD in solid organ transplant recipients.