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Case Reports in Transplantation
Volume 2018, Article ID 4863187, 5 pages
Case Report

Liver Transplant for Unusually Large Polycystic Liver Disease: Challenges and Pitfalls

1Department of Surgery, Division of Abdominal Transplant Surgery, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA
2Division of Gastroenterology and Hepatology, The University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA

Correspondence should be addressed to Chirag Sureshchandra Desai; ude.cnu.dem@iased_garihc

Received 6 December 2017; Accepted 4 January 2018; Published 1 February 2018

Academic Editor: Ryszard Grenda

Copyright © 2018 Pablo Serrano Rodriguez et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Patients with polycystic liver disease are described in the literature as both recipient and donor for liver transplant. Due to well-preserved liver function, it is often difficult for these patients to receive an organ. Livers of these patients are often large and heavier than a normal organ. We describe two cases who had exceedingly large livers, weighing 14 and 19 kg. To the best of our knowledge and search, these are some of the heaviest explanted livers, and one of the patients incidentally received a liver from a donor with ADPKD. The aim of this report is to discuss the challenges and pitfalls of evaluating and listing, technical aspect of the transplant, possibility of transplanting a liver from a donor with a genetic cystic disease to a cystic disease recipient, and the related literature with some highlights on the facts from UNOS/OPTN data.