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Figure 3: Immunohistochemical profile. (a) Cytokeratin AE1/ae3 stain showing a strong reactivity in epithelial component and focal expression is present at mesenchymal component (DAB, 100x). (b) Ki-67 nuclear positivity in both epithelial and mesenchymal component (DAB, 100x). (c and d) Estrogen and progesterone receptor expression. Multinucleated stromal cells showing nuclear positivity (Circle) (DAB, 400x). (e and f) p63 immunoreactivity in epithelial and stromal elements (DAB, 100x-200x).