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Case Reports in Urology
Volume 2012, Article ID 402513, 4 pages
http://dx.doi.org/10.1155/2012/402513
Case Report

Treatment of Locally Advanced Prostate Cancer: A Case Report and Narrative Review

1Institute of Health Economics and Clinical Epidemiology (IGKE), University Hospital of Cologne, 50924 Cologne, Germany
2Department of Radiotherapy, University Hospital Aachen, 52074 Aachen, Germany

Received 6 November 2012; Accepted 29 November 2012

Academic Editors: A. Marte, T. J. Murtola, T. Nomura, and S. Takahashi

Copyright © 2012 Frank Peinemann and Michael Pinkawa. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. Siegel, D. Naishadham, and A. Jemal, “Cancer statistics,” A Cancer Journal for Clinicians, vol. 62, no. 1, pp. 10–29, 2012. View at Google Scholar
  2. World Health Organization, “Chapter 3. tumours of the prostate,” in World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs, International Agency for Research on Cancer (IARC), Lyon, France; World Health Organization, Geneva, Switzerland, 2012. View at Google Scholar
  3. A. Heidenreich, M. Bolla, S. Joniau et al., Guidelines on Prostate Cancer, European Association of Urology (EAU), Arnhem, The Netherlands, 2012.
  4. A. Heidenreich, J. Bellmunt, M. Bolla et al., “EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease,” European Urology, vol. 59, no. 1, pp. 61–71, 2011. View at Publisher · View at Google Scholar · View at Scopus
  5. W. H. Cooner, B. R. Mosley, C. L. Rutherford Jr. et al., “Prostate cancer detection in a clinical urological practice by ultrasonography, digital rectal examination and prostate specific antigen,” Journal of Urology, vol. 143, no. 6, pp. 1146–1154, 1990. View at Google Scholar · View at Scopus
  6. L. Egevad, T. Granfors, L. Karlberg, A. Bergh, and P. Stattin, “Prognostic value of the Gleason score in prostate cancer,” British Journal of Urology International, vol. 89, no. 6, pp. 538–542, 2002. View at Publisher · View at Google Scholar · View at Scopus
  7. I. M. Thompson, D. K. Pauler, P. J. Goodman et al., “revalence of prostate cancer among men with a prostate-specific antigen level < or = 4.0 ng per milliliter,” The New England Journal of Medicine, vol. 350, no. 22, pp. 2239–2246, 2004. View at Google Scholar · View at Scopus
  8. NCCN, NCCN Guidelines for Patients: Prostate Cancer, Version 1, National Comprehensive Cancer Network (NCCN), Washington, DC, USA, 2011.
  9. D. Ulmert, A. M. Cronin, T. Björk et al., “Prostate-specific antigen at or before age 50 as a predictor of advanced prostate cancer diagnosed up to 25 years later: a case-control study,” BMC Medicine, vol. 6, article 6, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. A. J. Vickers, C. J. Savage, F. J. Bianco et al., “Surgery confounds biology: the predictive value of stage-, grade- and prostate-specific antigen for recurrence after radical prostatectomy as a function of surgeon experience,” International Journal of Cancer, vol. 128, no. 7, pp. 1697–1702, 2011. View at Publisher · View at Google Scholar · View at Scopus
  11. E. Xylinas, A. Daché, and M. Rouprêt, “Is radical prostatectomy a viable therapeutic option in clinically locally advanced (cT3) prostate cancer?” British Journal of Urology International, vol. 106, no. 11, pp. 1596–1600, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. V. Berge, T. Thompson, and D. Blackman, “Use of additional treatment for prostate cancer after radical prostatectomy, radiation therapy, androgen deprivation, or watchful waiting,” Scandinavian Journal of Urology and Nephrology, vol. 41, no. 3, pp. 198–203, 2007. View at Publisher · View at Google Scholar · View at Scopus
  13. M. D. Shelley, S. Kumar, B. Coles, T. Wilt, J. Staffurth, and M. D. Mason, “Adjuvant hormone therapy for localised and locally advanced prostate carcinoma: a systematic review and meta-analysis of randomised trials,” Cancer Treatment Reviews, vol. 35, no. 7, pp. 540–546, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. S. Kumar, M. Shelley, C. Harrison, B. Coles, T. J. Wilt, and M. D. Mason, “Neo-adjuvant and adjuvant hormone therapy for localised and locally advanced prostate cancer,” Cochrane Database of Systematic Reviews, no. 4, Article ID CD006019, 2006. View at Google Scholar · View at Scopus
  15. A. J. Stephenson, M. Bolla, A. Briganti et al., “Postoperative radiation therapy for pathologically advanced prostate cancer after radical prostatectomy,” European Urology, vol. 61, no. 3, pp. 443–451, 2012. View at Google Scholar
  16. T. Wiegel, D. Bottke, U. Steiner et al., “Phase III postoperative adjuvant radiotherapy after radical prostatectomy compared with radical prostatectomy alone in pT3 prostate cancer with postoperative undetectable prostate-specific antigen: ARO 96-02/AUO AP 09/95,” Journal of Clinical Oncology, vol. 27, no. 18, pp. 2924–2930, 2009. View at Google Scholar
  17. S. S. Chang and M. S. Cookson, “Impact of positive surgical margins after radical prostatectomy,” Urology, vol. 68, no. 2, pp. 249–252, 2006. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Steuber, A. Erbersdobler, M. Graefen, A. Haese, H. Huland, and P. I. Karakiewicz, “Comparative assessment of the 1992 and 2002 pathologic T3 substages for the prediction of biochemical recurrence after radical prostatectomy,” Cancer, vol. 106, no. 4, pp. 775–782, 2006. View at Publisher · View at Google Scholar · View at Scopus
  19. P. Gontero, G. Marchioro, R. Pisani et al., “Is radical prostatectomy feasible in all cases of locally advanced non-bone metastatic prostate cancer? Results of a single-institution study,” European Urology, vol. 51, no. 4, pp. 922–930, 2007. View at Google Scholar · View at Scopus
  20. C. Y. Hsu, S. Joniau, R. Oyen, T. Roskams, and H. van Poppel, “Outcome of surgery for clinical unilateral T3a prostate cancer: a single-institution experience,” European Urology, vol. 51, no. 1, pp. 121–129, 2007. View at Publisher · View at Google Scholar · View at Scopus
  21. H. Miyake, I. Sakai, K. I. Harada, I. Hara, and H. Eto, “Long-term results of adjuvant hormonal therapy plus radiotherapy following radical prostatectomy for patients with pT3N0 or pT3N1 prostate cancer,” International Journal of Urology, vol. 11, no. 6, pp. 397–401, 2004. View at Publisher · View at Google Scholar · View at Scopus
  22. R. K. Berglund, J. S. Jones, J. C. Ulchaker et al., “Radical prostatectomy as primary treatment modality for locally advanced prostate cancer: a prospective analysis,” Urology, vol. 67, no. 6, pp. 1253–1256, 2006. View at Publisher · View at Google Scholar · View at Scopus
  23. C. Y. Hsu, M. F. Wildhagen, H. van Poppel, and C. H. Bangma, “Prognostic factors for and outcome of locally advanced prostate cancer after radical prostatectomy,” British Journal of Urology International, vol. 105, no. 11, pp. 1536–1540, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. L. Mearini, A. Zucchi, E. Costantini, V. Bini, E. Nunzi, and M. Porena, “Outcomes of radical prostatectomy in clinically locally advanced N0M0 prostate cancer,” Urologia Internationalis, vol. 85, no. 2, pp. 166–172, 2010. View at Publisher · View at Google Scholar · View at Scopus
  25. G. Ploussard, M. A. Agamy, O. Alenda et al., “Impact of positive surgical margins on prostate-specific antigen failure after radical prostatectomy in adjuvant treatment-naive patients,” British Journal of Urology International, vol. 107, no. 11, pp. 1748–1754, 2011. View at Publisher · View at Google Scholar · View at Scopus
  26. S. Schelin, M. Madsen, E. Palmqvist, E. Mäkelä, C. Klintenberg, and G. Aus, “Long-term follow-up after triple treatment of prostate cancer stage pT3,” Scandinavian Journal of Urology and Nephrology, vol. 43, no. 3, pp. 186–191, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. A. M. Kamat, K. Babaian, M. R. Cheung et al., “Identification of factors predicting response to adjuvant radiation therapy in patients with positive margins after radical prostatectomy,” Journal of Urology, vol. 170, no. 5, pp. 1860–1863, 2003. View at Publisher · View at Google Scholar · View at Scopus
  28. I. C. Cho, W. A. Kwon, J. E. Kim et al., “Prostate volume has prognostic value only in pathologic T2 radical prostatectomy specimens,” Journal of Korean Medical Science, vol. 26, no. 6, pp. 807–813, 2011. View at Publisher · View at Google Scholar · View at Scopus