(a) Computed tomography (CT) before first temsirolimus administration. There are multiple metastatic tumors in liver. All tumors are enhanced weakly (64 Hounsfield units). (b) CT 2 months after temsirolimus administration. Most tumors shrink. (c) CT 5 months after temsirolimus administration. Metastatic tumors grow again. All tumors are enhanced strongly (137 Hounsfield units). (d) CT 3 weeks after sunitinib readministration. All tumors turned to be hypovascular again (67 Hounsfield units).
