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Case Reports in Urology
Volume 2013, Article ID 194690, 4 pages
Case Report

Radical Chemoradiotherapy for Urethral Squamous Cell Carcinoma: Two Case Reports and a Review of the Literature

Deansley Centre, Royal Wolverhampton Hospital, Wednesfield Road, Wolverhampton WV10 0QP, UK

Received 20 March 2013; Accepted 15 April 2013

Academic Editors: S.-S. Chen, A. Goel, G. L. Gravina, and F. Ramezanzadeh

Copyright © 2013 H. Coop et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Primary urethral squamous cell carcinoma is rare. Its management is particularly challenging owing to the paucity of evidence from randomised trials to inform practice. We report two male and female cases of squamous cell carcinoma of the urethra, which were treated with concomitant cisplatin and radiotherapy. These cases add to the body of case reports that have shown benefit for concomitant chemoradiotherapy in urethral squamous cell carcinoma. They also illustrate that single agent chemotherapy, namely, cisplatin, may be used successfully with limited toxicities.