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Case Reports in Urology
Volume 2016 (2016), Article ID 9016728, 4 pages
Case Report

Metastatic Granulosa Cell Tumor of the Testis: Clinical Presentation and Management

1Division of Urologic Surgery, Washington University School of Medicine, St. Louis, MO 63110, USA
2Department of Pathology, Washington University School of Medicine, St. Louis, MO 63110, USA

Received 29 February 2016; Accepted 20 April 2016

Academic Editor: Fumitaka Koga

Copyright © 2016 Anand Mohapatra et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Granulosa cell tumors (GCTs) of the testis are rare sex cord-stromal tumors that are present in both juvenile and adult subtypes. While most adult GCTs are benign, those that present with distant metastases manifest a grave prognosis. Treatments for aggressive GCTs are not well established. Options that have been employed in previous cases include retroperitoneal lymph node dissection (RPLND), radiation, chemotherapy, or a combination thereof. We describe the case of a 57-year-old man who presented with a painless left testicular mass and painful gynecomastia. Serum tumor markers (alpha fetoprotein, human chorionic gonadotropin, and lactate dehydrogenase) and computed tomography of the chest and abdomen were negative. The patient underwent left radical orchiectomy. Immunohistochemical staining was consistent with a testicular GCT. He underwent a left-template laparoscopic RPLND which revealed 2/19 positive lymph nodes. Final pathological stage was IIA. He remains free of disease 32 months after surgery.