Complaint of Testicular Discomfort in Patient with Esophageal Adenocarcinoma

Figure 3

Esophageal tissue (left): sheets of neoplastic cells with high nucleus/cytoplasm ratio and nuclear hyperchromasia and pleomorphism. Immunohistochemical staining was positive for monoclonal CEA and negative for p63, synaptophysin, and chromogranin, supporting a diagnosis of poorly differentiated adenocarcinoma (H&E; ×12.5). Testicular tissue (right): poorly differentiated and loosely cohesive carcinoma with predominantly solid and some focal glandular architecture demonstrating considerable pleomorphism. Adjacent seminiferous tubule (H&E; ×10).