Destructive Cholangitis in an Adult Jack Russell Terrier
Figure 2
Histopathological and immunohistological features of the liver. (a) Glisson’s capsule with brown pigmentations. HE. Bar = 250 μm. (b) Interlobular bile ducts and bile ductules were not observed, but many pigment-laden macrophages infiltrating Glisson’s capsule were present. HE. Bar = 50 μm. (c) The brown pigments contained within macrophages in Glisson’s capsule stained blue with Prussia blue stain. Bar = 50 μm. (d) There is no lumen formation composed of cytokeratin 19-positive cells in Glisson’s capsule. However, positivity for cytokeratin 19 is shown in the epidermoid cells at the boundary division between the Glisson’s capsule and hepatic lobule (arrowheads). IHC for cytokeratin 19. Bar = 50 μm.
