Case Report

A Case of Contagious Ecthyma (Orf Virus) in a Nonmanipulated Laboratory Dorset Sheep (Ovis aries)

Figure 6

Haired skin, lip commissure. Epithelial hyperplasia, necrosis, and loss with overlying serocellular crust ( ) composed of keratin, proteinaceous fluid, degenerate neutrophils, and numerous mixed bacteria. Insets: rarely keratinocytes demonstrate large clear cytoplasmic vacuoles (ballooning degeneration) (left) and contain one or more 2–10 µm round, brightly eosinophilic intracytoplasmic inclusion bodies (left and right, arrowheads). Hematoxylin and eosin stain, 20x objective.
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