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Case Reports in Veterinary Medicine
Volume 2013, Article ID 703732, 4 pages
http://dx.doi.org/10.1155/2013/703732
Case Report

Aniridia in Two Related Tennessee Walking Horses

1Large Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, 2407 River Drive, Knoxville, TN 37996, USA
2Small Animal Clinical Sciences, University of Tennessee, College of Veterinary Medicine, 2407 River Drive, Knoxville, TN 37996, USA
3Diagnostic and Biomedical Sciences, University of Tennessee, College of Veterinary Medicine, 2407 River Drive, Knoxville, TN 37996, USA

Received 26 April 2013; Accepted 23 May 2013

Academic Editors: L. Espino López, S. Hecht, F. Mutinelli, and S. Stuen

Copyright © 2013 Karen A. McCormick et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Aniridia in horses is rare and has previously been reported to be genetically transmitted in Belgian horses and Quarter horses. This paper describes the defect in 2 related Tennessee Walking horses, with special reference to new findings regarding the molecular genetics of ocular development and how they might relate to equine aniridia. In addition to aniridia, these 2 horses possessed additional ocular abnormalities including cataracts and dermoid lesions. Euthanasia was elected, and the eyes were examined histologically. Iris hypoplasia, atypical dermoids, and cataracts were confirmed in both horses. Due to the heritability of aniridia in horses, breeding of affected animals is not recommended.