Canadian Respiratory Journal
Volume 2, Suppl A, Pages 19A-23A
http://dx.doi.org/10.1155/1995/901037
NSAIDs in the Treatment of Adult Asthma: Sodium Cromoglycate and Nedocromil Sodium
Service de pneumologie et d’allergie, Hôpital du Saint-Sacrement, Québec, Québec, Canada
Copyright © 1995 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Among nonsteroidal anti-inflammatory drugs used in the treatment of adult asthma, sodium cromoglycate and nedocromil sodium are the most frequently prescribed. These medications have a similar efficacy profile in asthma although it has been suggested that nedocromil is more powerful than cromoglycate, particularly in its steroid sparing effects. Both drugs have been recommended as alternatives to steroids in the treatment of mild asthma. They are useful in the prevention of bronchospasm induced by exposure to allergens or to a variety of other stimuli. In comparison with theophylline or low dose inhaled steroids, cromoglycate and nedocromil have shown a similar antiasthmatic efficacy, although this is variable among patients.