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Canadian Respiratory Journal
Volume 11, Issue 6, Pages 414-424
Original Article

Reference Values of Pulmonary Function Tests for Canadian Caucasians

Carlos Gutierrez,1 R Heberto Ghezzo,2 Raja T Abboud,3 Manuel G Cosio,2 John R Dill,4 Richard R Martin,2 Dan S McCarthy,5 John LC Morse,6 and Noe Zamel1

1Tri–Hospital Service (Mount Sinai — Toronto General — Women’s College Hospitals), University of Toronto, Toronto, Ontario, Canada
2Hôpital du Sacré–Coeur, University of Montreal, Montreal, Quebec, Canada
3Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada
4Glace Bay Community Hospital, Glace Bay, Nova Scotia, Canada
5Respiratory Hospital University of Manitoba, Winnipeg, Manitoba, Canada
6St Joseph’s Hospital, McMaster University, Hamilton, Ontario, Canada

Copyright © 2004 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


A multicentre, cross-sectional study was carried out in six centres across Canada to establish a national standard for pulmonary function tests using healthy, lifetime nonsmokers, with each centre aiming to test 10 men and 10 women from each decade from 20 to 80 years of age. Data from each centre were used to derive prediction equations for each centre, and pooled data from all centres (total: 327 women and 300 men) were used to derive Canadian predicted equations. The predictive models were compared with three widely used published models for selected tests. It was found that, in general, the equations modelled for each centre could be replaced by the models obtained when pooling all data (Canadian model). Comparisons with the published references showed good agreement and similar slopes for most tests. The results suggest that pulmonary function test results obtained from different centres in Canada were comparable and that standards currently used remain valid for Canadian Caucasians.