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Canadian Respiratory Journal
Volume 12 (2005), Issue 3, Pages 123-127
http://dx.doi.org/10.1155/2005/563748
Original Article

Endobronchial Mimics of Primary Endobronchial Carcinoma: A Clinical Study of 25 Cases

Cynthia M Magro1 and Patrick Ross2

1Department of Pathology, The Ohio State University, Columbus, Ohio, USA
2Division of Cardiothoracic Surgery, The Ohio State University, Columbus, Ohio, USA

Copyright © 2005 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

While endobronchial lesions that present with symptoms of obstruction may be reflective of primary bronchogenic malignancy, there have been a number of reports of bronchial lesions other than primary bronchogenic carcinoma simulating primary endobronchial epithelial malignancy clinically. Twenty-five cases of symptomatic endobronchial disease were encountered with pathological assessment demonstrating an endobronchial process other than carcinoma, representing metastatic disease (breast, colon, renal, head and neck origin), fungal infection, Hodgkin's lymphoma, primary bronchogenic melanoma, lipoma, broncholith and inflammatory pseudopolyp. The present report underscores the potential pathogenetic heterogeneity encountered in lesions presenting with signs and symptoms of endobronchial obstruction, emphasizing the critical role of biopsy for establishing a definitive diagnosis.