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Canadian Respiratory Journal
Volume 13, Issue 7, Pages 381-383
Pediatric Case Report

Recurrent Respiratory Papillomatosis Causing Chronic Stridor and Delayed Speech in an 18-Month-Old Boy

Adel Alharbi,1 Derek Drummond,2 Alfredo Pinto,3 and Valerie Kirk1

1Department of Paediatrics, Division of Respiratory Medicine, University of Calgary, Calgary, Alberta, Canada
2Department of Paediatric General Surgery, Division of Otolaryngology, University of Calgary, Calgary, Alberta, Canada
3Department of Pathology, University of Calgary, Calgary, Alberta, Canada

Copyright © 2006 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Recurrent respiratory papillomatosis is a relatively uncommon disease that presents clinically with symptoms ranging from hoarseness to severe dyspnea. Human papilloma virus types 6 and 11 are important in the etiology of papillomas and are most probably transmitted from mother to child during birth. Although spontaneous remission is frequent, pulmonary spread and/or malignant transformation resulting in death has been reported. CO2 laser evaporation of papillomas and adjuvant drug therapy using lymphoblastoid interferon-alpha are the most common treatments. However, several other treatments have been tried, with varying success. In the present report, a case of laryngeal papillomatosis presenting with chronic stridor and delayed speech is described.