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Canadian Respiratory Journal
Volume 17 (2010), Issue 1, Pages e23-e24
Case Report

Endoscopic Sealing of Bronchopleural Fistulas with Submucosal Injection of a Tissue Expander: A Novel Technique

Cayo García-Polo, Antonio León-Jiménez, Jose Luis López-Campos, Aurelio Arnedillo, Enrique González-Moya, Juan José Fernández-Berni, and Juan Manuel Gómez

Sección de Neumología y Alergia, Hospital Universitario Puerta del Mar, Cádiz, Spain

Copyright © 2010 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


The occurrence of a bronchopleural fistula (BPF) continues to represent a challenging management problem, and is associated with high morbidity and mortality. A novel and successful technique that uses submucosal injection of a tissue expander for bronchoscopic occlusion of BPFs has been designed. This method may be used either alone or in combination with bronchoscopic instillation of n-butyl-cyanoacrylate glue. The occlusion technique is described, with a presentation of two patients who were successfully treated with this method. The submucosal injection of a tissue expander is an effective, economical and minimally invasive technique for managing BPFs.