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Canadian Respiratory Journal
Volume 18, Issue 6, Pages e86-e88
Case Report

Granulomatous Pneumocystis Jiroveci Pneumonia Associated with Immune Reconstituted HIV

Natasha F Sabur,1 Margaret M Kelly,2 M John Gill,1 Martha D Ainslie,3 and Sachin R Pendharkar1

1Department of Medicine, University of Calgary, Calgary, Alberta, Canada
2Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta, Canada
3Department of Respirology, University of Manitoba, Winnipeg, Manitoba, Canada

Copyright © 2011 Hindawi Publishing Corporation. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Pneumocystis jiroveci pneumonia uncommonly presents with pulmonary nodules and granulomatous inflammation. An unusual case of granulomatous P jiroveci pneumonia in an HIV patient with a CD4+ lymphocyte count of greater than 200 cells/mm3, occurring in the context of immune reconstitution with highly active antiretroviral therapy, is described. The case highlights the importance of establishing this diagnosis to institute appropriate therapy.