A New Scale to Assess the Severity and Prognosis of Pulmonary Alveolar Proteinosis
Table 5
The characteristics of the groups of survivors and nonsurvivors.
Parameter
All patients
Nonsurvivors
Survivors
value
Subjects, number
101
7
94
Sex, M/F, number
71/30
5/2
66/28
0.980
Age, y
48.7 ± 11.2
54.4 ± 9.9
48.3 ± 11.2
0.174
Smoking history, number (%)
42 (41.6%)
3 (42.9%)
39 (41.4%)
0.944
Occupational exposure, number (%)
50 (49.5%)
4 (57.1%)
46 (48.9%)
0.842
Onset of symptoms, y
47.3 ± 11.0
53.0 ± 9.3
46.8 ± 11.0
0.165
Course of disease, m
19.8 ± 33.3
19.7 ± 15.6
19.8 ± 34.4
0.997
Symptoms, number (%)
87 (86.1%)
7 (100%)
80 (85.1%)
<0.001
PaO2, mmHg
75.8 ± 17.7
66.4 ± 21.0
76.5 ± 17.4
0.127
HRCT score
17.3 ± 7.8
24.7 ± 7.3
16.7 ± 7.6
0.008
FVC, % predicted
80.0 ± 15.2
63.2 ± 13.8
81.3 ± 14.6
0.002
FEV1, % predicted
80.2 ± 15.1
63.3 ± 14.2
81.5 ± 14.5
0.002
FEV1/FVC
84.7 ± 6.4
89.1 ± 3.4
84.4 ± 6.5
0.058
DLCO, % predicted
73.9 ± 21.9
52.9 ± 10.9
75.5 ± 21.7
0.001
Data are presented as (%) or mean ± SD unless otherwise stated. DLCO: single-breath diffusing capacity of carbon monoxide; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; HRCT: high resolution computed tomography; PaO2: arterial partial pressure of oxygen.
