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Canadian Respiratory Journal
Volume 2016, Article ID 3564341, 12 pages
Research Article

Identification of Susceptibility Genes of Adult Asthma in French Canadian Women

1Institut Universitaire de Cardiologie et de Pneumologie de Québec, Quebec City, QC, Canada G1V 4G5
2Département des Sciences Fondamentales, Université du Québec à Chicoutimi, Chicoutimi, QC, Canada G7H 2B1
3The University of British Columbia Center for Heart Lung Innovation, St. Paul’s Hospital, Vancouver, BC, Canada
4University of British Columbia Department of Medicine, Division of Respiratory Medicine, Vancouver, BC, Canada V5Z 1M9
5University Medical Center Groningen, GRIAC Research Institute, University of Groningen, Groningen, Netherlands
6Merck Research Laboratories (MRL), Seattle, WA, USA
7Department of Molecular Medicine, Laval University, Quebec City, QC, Canada G1V 0A6

Received 17 July 2015; Accepted 5 December 2015

Copyright © 2016 Jean-Christophe Bérubé et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Supplementary Material

Supplementary materials contain additional details about the methodologies. It also contains two figures showing the pool-GWAS design (Suppl. Figure 1) and the asthma genetic association results stratified by sex in the QCCCAC for the 38 genotyped SNPs (Suppl. Figure 2). Eight supplementary tables are also available showing results for 38 SNPs tested by individual genotyping in 299 allergic cases and 154 allergic controls (Suppl. Table 1), completed results for the 21 SNPs associated with asthma and SNPs in LD (Suppl. Table 2), most significant lung eQTL (Suppl. Table 3), in silico analyses results (Suppl. Tables 4 to 6), and results from the SLSJ asthma family collection (Suppl. Tables 7 and 8).

  1. Supplementary Material