Research Article
Identification of Susceptibility Genes of Adult Asthma in French Canadian Women
Table 3
SNPs ranked in the top 2000 of the pooled GWAS that are near or within asthma candidate genes and selected for individual genotyping.
| dbSNP ID | Chromosome | Rank | Silhouette score | Near candidate gene(s) |
| rs7576929 | 2q35 | 56 | 0.618 | SLC11A1 | rs3094738 | 6p21.33 | 85 | 0.593 | MICB | rs6934016 | 6q25.1 | 100 | 0.585 | ESR1 | rs5250 | 14q12 | 115 | 0.577 | CMA1 | rs17016738 | 3p24.2 | 220 | 0.544 | RARB | rs17453235 | 2q14.1 | 290 | 0.531 | DPP10 | rs7131715 | 12q13.12 | 305 | 0.528 | AQP5 | rs3097657 | 6p21.32 | 371 | 0.517 | HLA-DPB1 | rs2071596 | 6p21.33 | 373 | 0.517 | LTA, MICB, NCR3, TNF | rs2858769 | Xp11.23 | 515 | 0.502 | TIMP1 | rs9874200 | 3q26.2 | 562 | 0.497 | MECOM | rs10932034 | 2q33.2 | 567 | 0.497 | ICOS | rs2904774 | 6p21.33 | 601 | 0.494 | MICB | rs17466945 | 1q32.1 | 626 | 0.492 | CHI3L1 | rs803010 | 14q22.1 | 723 | 0.484 | PTGDR, PTGER2 | rs1889371 | 14q32.2 | 742 | 0.482 | BDKRB2 | rs10864910 | 2q13 | 786 | 0.479 | IL1RN | rs241423 | 6p21.32 | 811 | 0.478 | TAP1 | rs17160155 | 11q13.5 | 881 | 0.473 | LRRC32 | rs3135195 | 6p21.32 | 961 | 0.468 | HLA-DPB1 | rs3093665 | 6p21.33 | 970 | 0.467 | AIF1, LTA, NCR3, TNF | rs17801353 | 12p13.31 | 981 | 0.466 | C3AR1 | rs6657275 | 1q41 | 1017 | 0.464 | TGFB2 |
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Ranking based on the pooled GWAS.
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