Research Article

The Characteristics of Treated Pulmonary Arterial Hypertension Patients in Ontario

Table 1

Baseline characteristics and demographics of PAH cases in Ontario as of April 1, 2011.

TotalAge < 65Age ≥ 65 value
Age < 65 versus age ≥ 65

Female ( (%))251 (77%)127 (77%)124 (77%)0.992
Age (mean, SD)59.4 (20.3)43.4 (15.8)75.7 (6.7)<0.001
Rural location of residence ( (%))39 (12%)17 (10.3%)22 (13.7%)0.350
Income quintile ( (%))
 1 (lowest)77 (23.6%)42 (25.5%)35 (21.7%)0.430
 252 (16%)29 (17.6%)23 (14.3%)0.417
 364 (19.6%)31 (18.8%)33 (20.5%)0.698
 481 (24.9%)37 (22.4%)44 (27.3%)0.306
 5 (highest)52 (16%)26 (15.8%)26 (16.2%)0.923
Comorbidities ( (%))
 Cardiovascular disease312 (95.7%)156 (94.6%)156 (96.9%)0.296
 Heart failure 72 (22.1%)33 (20%)39 (24.2%)0.358
 Atrial fibrillation/flutter 41 (12.6%)9 (5.5%)32 (19.9%)0.001
 Respiratory disease154 (47.2%)56 (33.9%)98 (60.9%)<0.001
 Chronic obstructive pulmonary disease 147 (45.1%)55 (33.3%)92 (57.1%)<0.001
 Connective tissue disease47 (14.4%)27 (16.4%)20 (12.4%)0.311
Other conditions
 Diabetes 79 (24.2%)27 (16.4%)52 (32.3%)<0.001
 Thyroid disease 17 (5.2%)10 (6.1%)7 (4.4%)0.487
Drug use (past 3 years) ( (%))
 Antihypertensive145 (44.5%)49 (29.7%)96 (59.6%)<0.001
 Calcium channel blockers 75 (23%)19 (11.5%)56 (34.8%)<0.001
 Oral anticoagulants 125 (38.3%)53 (32.1%)72 (44.7%)0.019
 Diuretics 189 (58.0%)73 (44.2%)116 (72.1%)<0.001
 Digoxin 25 (7.7%)9 (5.5%)16 (9.9%)0.128