Clinical Outcomes Associated with Home Mechanical Ventilation: A Systematic Review

Table 2

Patient characteristics.

Study	Age (mean)		Male ()		NMD ()	RTD ()	OHS ()	Other^‡‡ ()	NIV ()
Bourke et al. [3]	63		24	41	41	NA	NA	NA	22
Tsolaki et al. [6]	65^†		61	91	11	17	28	35	91
Windisch et al. [7]	59^†		49	85	17	29	9	27	85
Dellborg et al. [8]	63^‡		15^‡	35^‡	12^‡	21^‡	NA	2^‡	35
	58		4	11	7	4		0
Farrero et al. [9]	77		20	43	9	26	8	0	43
Gonzalez et al. [10]	57		NR	16	NA	16	NA	NA	16
Janssens et al. [11]	63^†		NR	211	40	42	71	58	211
Nauffal et al. [12]	50^†		33	62	27	35	NA	NA	62
Hein et al. [13]	56		16	27	8	8	NA	11	NR
Bach et al. [14]	NR		NR	684	650	19	3	12	636
Janssens et al. [15]	79		2	6	0	4	1	1	6
Chatwin et al. [16]	46		642	1211	NR	NR	NR	NR	1199
Budweiser et al. [17]	63		146	231	15	49	69	98	226
Marchese et al. [18]	58		54	77	41	8	3	25	0
Evans et al. [19]	45		NR	12	12	NA	NA	NA	0
Chang et al. [20]	55		24	45	7	6	27	3	39
Fernández-Álvarez et al. [21]	61		34	66	10	11	27	18	64
López-Campos et al. [22]	62		58	115	18	45	37	15	115
Vitacca et al. [23]	67		562	792	375	128	NA	289	634
Tsara et al. [24]	61		NR	50	15	0	6	29	44
Kaub-Wittemer et al. [25]	61		42	53	53	NA	NA	NA	32
Markström et al. [26]	59		40	91	49	13	0	29	55
van Kesteren et al. [27]	34		24	38	34	4	NA	NA	12
Sevick and Bradham [28]	45		NR	277	177	0	4	96	48
Moss et al. [29]	59		34	50	50	NA	NA	NA	7
Bötel et al. [30]	NA		NA	16	16	NA	NA	NA	NR
Aggregate data		60	1880	4425	1687	481	293	748	3682
	%^††	NA	59	100	53	15	9	23	85

, clinically evaluable population; NIV, noninvasive ventilation; NR, not reported.
Age >75 exclusion criteria. ^†Value based on mean age data provided for each disease state. ^‡Cohort who survived to 9 mo. Cohort who survived to 8 y. Age >75 inclusion criteria. Median. Several studies grouped RTD with NMD; ^††% aggregate proportion was based on total clinically evaluable population where both the numerator and denominator were available within the study. ^‡‡Including lung disease.