Clinical Outcomes Associated with Home Mechanical Ventilation: A Systematic Review

Table 4

Hospitalization rates before and after HMV.

Study	Disease state		Before	After^†
			#admissions/y	#admissions/y
Windisch et al. [7]	NMD, RTD, COPD, OHS	85	NR	0.1
Nauffal et al. [12]	NMD	27	1.1 (1.2)	0.3 (1.2)
	RTD	35	1.2 (1.8)	0.8 (1.2)
Farrero et al. [9]	NMD, RTD, OHS	43	2.2 (2.4)	0.5 (0.6)
Bach et al. [14]	NMD, RTD	654	1.5 (2.5)^‡	<0.6
Vitacca et al. [23]	NMD	375	NR	0.5 (0.4)
	RTD	128	NR	0.8 (0.5)
			d in hospital/pt/y	d in hospital/pt/y
Tsolaki et al. [6]	NMD	11	NR	2.4 (NR)
	RTD	17	NR	0
	OHS	28	NR	3.8 (5.7)
Janssens et al. [11, 15]	NMD, RTD	77	22 ()	17 ()
	OHS	32	26 ()	17 ()
Gonzalez et al. [10]	RTD	16	10.9 (13.3)	0

d, day; pt, patient; NMD, neuromuscular disorders; NR, not reported; OHS, obesity hypoventilation syndrome; RTD, restrictive thoracic diseases; y, year.
Mean (SD) based on 3-month minimum duration. ^†Mean (SD) based on first year of follow-up; ^‡204 high risk patients (defined as beginning from the first episode of pneumonia or hospitalization for respiratory failure until treatment with oxygen or mechanical ventilation). Aggregate data was not available and was instead reported by method of ventilation. For all methods hospitalization rates were <0.6. Median (SD).