Differentiating Malignant from Tubercular Pleural Effusion by Cancer Ratio Plus (Cancer Ratio: Pleural Lymphocyte Count)

Table 3

Cut-off for cancer ratio (serum LDH : pleural ADA ratio).

Cut-off level	Sensitivity (95% CI)	Specificity (95% CI)	PPV (95% CI)	NPV (95% CI)	PLR (95% CI)	NLR (95% CI)
>10	0.97 (0.90–0.99)	0.26 (0.13–0.44)	0.76 (0.67–0.84)	0.81 (0.47–0.96)	3.2 (2.2–4.6)	0.22 (0.06–0.80)
>20	0.95 (0.87–0.98)	0.85 (0.68–0.94)	0.94 (0.86–0.97)	0.87 (0.70–0.96)	16 (6.8–37.5)	0.13 (0.05–0.34)
>30	0.89 (0.80–0.94)	0.94 (0.78–0.98)	0.97 (0.90–0.99)	0.78 (0.61–0.88)	37.5 (9.5–147.3)	0.28 (0.15–0.50)
>40	0.76 (0.65–0.84)	0.94 (0.78–0.98)	0.96 (0.88–0.99)	0.61 (0.47–0.74)	32 (8.1–125.3)	0.62 (0.43–0.90)
>50	0.66 (0.55–0.76)	0.94 (0.78–0.98)	0.96 (0.87–0.99)	0.53 (0.40–0.66)	28 (7.1–109.3)	0.87 (0.64–1.18)
>60	0.57 (0.45–0.67)	0.97 (0.82–0.99)	0.97 (0.87–0.99)	0.47 (0.35–0.60)	48 (6.8–334.1)	1.09 (0.84–1.41)