Respiratory Presentation of Pediatric Patients in the 2014 Enterovirus D68 Outbreak
Table 2
Clinical presentation of hospitalized children with EV-D68.
Clinical presentation
(%)
Month of presentation (total )
August
1 (3)
September
5 (15)
October
25 (74)
November
3 (9)
Parent reported symptoms at presentation (total )
Shortness of breath
28 (82)
Cough
28 (82)
Rhinorrhea/congestion
24 (71)
Fever
21 (62)
Wheeze
15 (44)
Vomiting
11 (32)
Vital signs at presentation (total )
Tachypnea
27 (79)
Tachycardia
20 (59)
Oxygen saturation <92%
20 (59)
Fever ≥ 38°C
4 (12)
Auscultatory findings (total )
Decreased air entry
30 (88)
Wheeze
26 (76)
Crackles
12 (35)
Silent chest
9 (26)
PRAM score at presentation (total )
0–3 (mild)
0 (0)
4–7 (moderate)
6 (27)
8–12 (severe)
16 (73)
Laboratory findings (total )
Leukocytosis
12 (52)
Neutrophilia
17 (74)
Lymphopenia
19 (83)
Copathogens identified on PCR testing of nasopharyngeal washings (total )
11 (42)
Chest X-ray findings (total )
Normal chest X-ray
4 (14)
Minor patchy changes
6 (21)
Major patchy changes
6 (21)
Lobar changes
1 (3)
Peribronchial thickening
11 (38)
Hyperinflation
9 (31)
Vital sign parameters were defined according to norms for age as per the Hospital of Sick Children’s Handbook of Pediatrics [15]. As defined by BCCH’s laboratory reference values for age.
