Research Article
The Role of Open Lung Biopsy in Critically Ill Patients with Hypoxic Respiratory Failure: A Retrospective Cohort Study
Table 1
Baseline clinical characteristics of cohort of patients who underwent an open lung biopsy.
| | | Total cohort (76) |
| | Age (IQR) | 63 (56–71) | | Male sex, (%) | 41 (54.0) | | APACHE II (IQR) | 22 (18–27) | | PaO2/FiO2 (IQR) | 141 (90–174) | | Vasopressor use, (%) | 6 (7.9) | | Mechanical ventilation on 1st day of ICU admission, (%) | 51 (67.2) | | Invasive | 16 (21.1) | | Noninvasive | 35 (46.1) | | Comorbidities, (%) | | | Lung disease | 27 (35.5) | | Hypertension | 28 (36.8) | | Diabetes | 23 (30.3) | | Malignancy | 20 (26.3) | | Solid organ | 6 (7.9) | | Hematological | 14 (18.4) | | Chronic renal failure | 12 (15.8) | | Dialysis dependent | 6 (7.9) | | Immunosuppressives prior to ICU admission, (%) | 20 (26.3) | | Medication received in ICU prior to biopsy, (%) | | | Steroid | 53 (69.7) | | Antibiotics | 74 (97.4) | | Antiviral | 12 (15.8) | | Antifungal | 16 (21.1) | | Imaging pattern, (%) | | | Ground glass opacification | 65 (85.5) | | Nodules | 7 (9.2) | | Pleural effusion | 18 (23.7) | | Other | 11 (14.5) | | Days from admission to open lung biopsy (IQR) | 2 (1–7) |
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µ: as seen on computed tomography by a trained pulmonologist.
IQR: interquartile range.
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