Mechanical Ventilation during Extracorporeal Membrane Oxygenation in Patients with Acute Severe Respiratory Failure

Table 1

Sliding scale of esophageal pressure-guided titration of PEEP. The table was adapted from [59]. Ventilator setting is adjusted in one column at a time to keep the partial pressure of arterial oxygen (PaO₂) between 55 and 120 mmHg. Alternatively, the oxygen saturation, as measured by pulse oximeter, is kept between 88 and 98% by using the ventilator settings in one column at a time. The positive end-expiratory pressure (PEEP) is set at such a level that transpulmonary pressure during end-expiratory occlusion (PLexp) stays between 0 and 10 cmH₂O and keeps transpulmonary pressure during end-inspiratory occlusion at less than 25 cmH₂O.

FiO2	0.4	0.5	0.5	0.6	0.6	0.7	0.7	0.8	0.8	0.9	0.9	1.0
Plexp	0	0	2	2	4	4	6	6	8	8	10	10