Effect of Antipyretic Therapy on Mortality in Critically Ill Patients with Sepsis Receiving Mechanical Ventilation Treatment
Table 1
Comparisons between survivors and nonsurvivors.
Variables
Overall ()
Survivors ()
Nonsurvivors ()
Age (years)
66.1 (52.0, 77.5)
64.6 (50.9, 76.6)
71.3 (58.1, 81.2)
<0.001
SAPS-1
17 (14, 20)
16 (13, 20)
19 (16, 23)
<0.001
SOFA
8 (6, 11)
8 (6, 10)
10 (7, 14)
<0.001
Lactate level
0.84 ± 0.76
0.85 ± 0.79
0.75 ± 0.62
0.0002
Sex (male, %)
4866 (55.9)
4032 (56.1)
834 (54.8)
0.36
Care unit (%)
<0.001
MICU
3567 (40.9)
2801 (39.0)
766 (50.3)
SICU
621 (7.1)
546 (7.6)
75 (4.9)
CCU
1646 (18.9)
1293 (18.0)
353 (23.2)
CSRU
2877 (33.0)
2548 (35.4)
329 (21.6)
External cooling (, %)
892 (10.2)
686 (9.5)
206 (13.5)
<0.001
Drug cooling (, %)
652 (7.5)
531 (7.4)
121 (7.9)
0.49
Any antipyretic (, %)
1385 (15.9)
1102 (15.3)
283 (18.6)
0.002
MICU, medical intensive care unit; SICU, surgical intensive care unit; CCU, coronary care unit; CSRU, cardiac surgery recovery unit; SAPS, Simplified Acute Physiology Score; SOFA, Sequential Organ Failure Assessment.
