Hypercapnic Ventilatory Response in the Weaning of Patients with Prolonged Mechanical Ventilation
Table 1
Clinical characteristics of enrolled subjects.
Characteristic
All ()
Weaning success ()
Weaning failure ()
value
Age, mean ± SD years
74.3 ± 14.9
70.6 ± 15.3
82.5 ± 10.3
.034
Male, number (%)
19 (59.4%)
14 (63.6%)
5 (50%)
.467
Height, mean ± SD cm
160.1 ± 10.7
161.6 ± 11.1
156.6 ± 9.3
.222
Body mass index, mean ± SD kg/m2
22.7 ± 4.5
22.8 ± 4.8
22.5 ± 3.8
.848
Transfer from medical ICU, number (%)
28 (87.5%)
20 (90.9%)
8 (80.0%)
.387
Tracheostomy, number (%)
8 (25.0%)
5 (22.7%)
3 (30.0%)
.660
APACHE II score
20.7 ± 6.1
20.3 ± 6.5
21.5 ± 5.2
.617
Ventilation-use days till drive test, mean ± SD day
31.4 ± 6.3
29.5 ± 5.3
35.5 ± 6.6
.011
Hemoglobin, mean ± SD g/dL
9.86 ± 1.41
9.82 ± 1.56
9.95 ± 1.08
.811
Albumin, mean ± SD g/dL
2.81 ± 0.52
2.84 ± 0.52
2.76 ± 0.54
.710
TSH, mean ± SD IU/mL
2.49 ± 1.89
2.19 ± 1.99
3.11 ± 1.59
.215
Free-T4, mean ± SD ng/dL
1.14 ± 0.32
1.12 ± 0.28
1.19 ± 0.41
.551
Reason for admission
Pneumonia, number (%)
15 (53.1%)
8 (36.4%)
7 (70.0%)
.077
AECOPD, number (%)
2 (6.3%)
2 (9.1%)
0 (0.0%)
.325
Congestive heart failure, number (%)
4 (12.5%)
2 (9.1%)
2 (20.0%)
.387
Myocardial infarction, number (%)
1 (3.1%)
1 (4.5%)
0 (0.0%)
.493
Cerebrovascular disease, number (%)
6 (18.8%)
6 (27.3%)
0 (0.0%)
.067
Ventricular tachycardia, number (%)
1 (3.1%)
1 (4.5%)
0 (0.0%)
.493
Urinary tract infection, number (%)
1 (3.1%)
1 (4.5%)
0 (0.0%)
.493
Burn, number (%)
1 (3.1%)
0 (0.0%)
1 (10.0%)
.132
Gastrointestinal bleeding, number (%)
1 (3.1%)
1 (4.5%)
0 (0.0%)
.493
APACHE II: Acute Physiology and Chronic Health Evaluation II; ventilation-use days till drive test: the duration time from the first day of mechanical ventilation use to the day of hypercapnic challenge test; AECOPD: chronic obstructive pulmonary disease with acute exacerbation; denotes statistical significance with .
