Comparison of Different Disease-Specific Health-Related Quality of Life Measurements in Patients with Long-Term Noninvasive Ventilation
Table 1
Baseline characteristics of 56 patients using noninvasive ventilation.
Characteristics
Total ()
COPD ()
Tb ()
Age, years
73 ± 8
70 ± 8
76 ± 7
BMI, kg/m2
20.5 ± 3.7
20.6 ± 3.8
20.4 ± 3.8
Cumulative smoking, pack-years
29 ± 34
50 ± 31
12 ± 26
FEV1, % predicted
29.9 ± 10.6
25.7 ± 10.3
33.0 ± 10.3
FVC, % predicted
45.7 ± 18.7
56.1 ± 22.7
38.1 ± 11.0
PaO2, kPa
10.7 ± 2.2
10.2 ± 2.2
11.1 ± 2.2
PaCO2, kPa
7.7 ± 1.4
7.5 ± 1.5
7.9 ± 1.4
Base excess, mmol/L
5.4 ± 3.4
4.8 ± 3.0
6.0 ± 3.6
mMRC dyspnea
2.3 ± 1.1
2.3 ± 1.0
2.3 ± 1.1
HADS anxiety
5.6 ± 3.7
5.5 ± 3.9
5.7 ± 3.6
HADS depression
7.4 ± 3.8
7.3 ± 3.5
7.5 ± 4.0
SRI respiratory complaints
62.3 ± 21.1
61.0 ± 21.2
62.5 ± 21.5
SRI physical functioning
52.1 ± 19.2
55.3 ± 17.3
50.5 ± 20.7
SRI attendant symptoms and sleep
61.3 ± 16.8
58.4 ± 18.1
63.0 ± 16.0
SRI social relationships
53.5 ± 17.6
55.6 ± 15.4
51.8 ± 20.0
SRI anxiety
54.2 ± 24.3
55.0 ± 24.0
52.7 ± 25.4
SRI psychological well-being
54.3 ± 17.0
55.1 ± 18.0
53.8 ± 17.0
SRI social functioning
54.5 ± 21.1
56.1 ± 18.9
54.0 ± 23.3
SRI summary
56.0 ± 15.3
56.6 ± 14.7
55.5 ± 16.4
MRF-26 daily activities
43.2 ± 30.5
39.8 ± 28.4
44.9 ± 31.9
MRF-26 perceived disability
52.7 ± 28.3
48.4 ± 26.9
54.3 ± 29.5
MRF-26 total
48.0 ± 26.7
43.8 ± 22.8
49.9 ± 29.1
SGRQ symptoms
50.4 ± 22.1
50.9 ± 23.6
49.6 ± 22.1
SGRQ activities
74.1 ± 17.4
75.7 ± 16.4
72.8 ± 18.5
SGRQ impacts
44.6 ± 22.4
45.3 ± 23.4
43.0 ± 22.2
SGRQ total
54.5 ± 18.5
55.4 ± 19.1
53.1 ± 18.5
Theoretical scores range from 0 to 4 in the mMRC, 0 to 21 in the HADS, and 0 to 100 in the SRI, MRF-26, and SGRQ. For the SRI, minimum scores indicate poor status, and for the mMRC, HADS, MRF-26, and SGRQ, maximum scores indicate poor status; BMI = body mass index; COPD = chronic obstructive pulmonary disease; Tb = pulmonary tuberculosis sequelae; FEV1 = forced expiratory volume in one second; FVC = forced vital capacity; PaO2 = arterial oxygen pressure; PaCO2 = arterial carbon dioxide pressure; mMRC = modified Medical Research Council; HADS = Hospital Anxiety and Depression Scale; SRI = Severe Respiratory Insufficiency; MRF = Maugeri Respiratory Failure; SGRQ = St. George’s Respiratory Questionnaire.
