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Inhaler | Mechanism | Advantages | Common errors |
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pMDI | Drug suspended/dissolved in propellant | (i) Portable (ii) Multiple metered dose (iii) No contamination of dose (iv) Press and breath requires coordination (v) Quick and easy to use | (i) Inhaler not shaken before use (ii) Inhaler not primed (iii) Incorrect positioning (upright) (iv) Full exhalation prior to dosing (v) Coordination of actuation and inhalation (vi) Poor inhalation technique (vii) Breath hold not long enough |
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pMDI + spacer | Drug suspended/dissolved in propellant | (i) Less coordination required than for pMDI (ii) Larger doses delivered (iii) Good lung deposition | (i) Inhaler not shaken before use (ii) Inhaler not primed (iii) Incorrect positioning (upright) (iv) Full exhalation prior to dosing (v) Delay between actuation and inhalation (vi) Poor inhalation technique (vii) Breath hold not long enough (viii) Poor maintenance of spacer |
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BA-MDI | (i) Drug suspended in propellant (ii) Breath-actuated delivery | (i) Portable (ii) Multiple metered dose (iii) No contamination of dose (iv) No coordination required (v) Quick and easy to use | (i) Inhaler not shaken before use (ii) Inhaler not primed (iii) Incorrect positioning (upright) (iv) Full exhalation prior to dosing (v) Poor inhalation technique (vi) Breath hold not long enough |
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DPI | Breath-actuated delivery | (i) Portable (ii) No coordination required (iii) Quick and easy to use | (i) Incorrect positioning (upright) (ii) Dose not prepared correctly (iii) Full exhalation prior to dosing (iv) Inhalation not forceful enough to actuate dose correctly (v) Breath hold not long enough (vi) Repeated procedures may be needed to administer full dose (vii) Inhaler not stored correctly |
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SMI | (i) Aqueous solution (ii) Aerosol delivered by compressed spring | (i) Portable (ii) No coordination required (iii) Slow-moving aerosol cloud (iv) Higher lung deposition than pMDI | (i) Full exhalation prior to dosing (ii) Poor inhalation technique (iii) Breath hold not long enough |
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Nebulizers | (i) Aqueous solution (ii) Aerosol produced by air jet or ultrasonic vibrations | (i) Can be used at any age (ii) Slow-moving aerosol cloud (iii) Tidal breathing | (i) Dose not prepared correctly (ii) Poor maintenance increases risk of bacterial contamination |
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