Effects of Fasudil on Patients with Pulmonary Hypertension Associated with Left Ventricular Heart Failure with Preserved Ejection Fraction: A Prospective Intervention Study

Table 3

Effect of fasudil on SpO₂, NT-pro-BNP, and 6MWD.

Variable	PPH (n = 23)			RPH (n = 35)
	Pretreatment	Posttreatment		Pretreatment	Posttreatment
SpO2 (%)	92.89 ± 3.97	93.15 ± 5.13	0.071	91.30 ± 4.68	93.07 ± 4.80	0.052
NT-pro-BNP (ng/ml) (min, max)	3664 (789, 21150)	1149 (750, 4651)	0.031	3980 (1312, 24000)	1287 (155, 8210)	0.004
6MWD (m)	361.75 ± 50.24	401.34 ± 59.56	0.042	345.60 ± 44.55	400.7 ± 59.41	0.001

Normally distributed data are presented as mean ± standard deviation; nonnormally distributed data are presented as minimum and maximum; normally distributed variables were evaluated using Student’s t-test; nonnormally distributed data were tested by the Wilcoxon test; ; 6MWD, 6-minute walking distance; the change from baseline,.