Adrenal Insufficiency in Cystic Fibrosis: A Rare Phenomenon?
Table 1
Clinical characteristics of patients with CF according to their adrenal function .
Sufficient
Insufficient
value
Demographic
Number of patients
36
33
Sex (% men)
41.7
48.5
0.572
Age (years)
30.0 (19.0–67.0)
28.0 (19.0–55.0)
0.648
Weight (kg)
54.1 (42.3–83.9)
61.0 (41.1–79.1)
0.084
BMI (kg/m2)
20.9 (17.5–28.6)
21.6 (17.1–27.5)
0.079
Genotype (% yes)
Homozygote delF508
58.3
60.6
Heterozygote delF508
38.9
30.3
0.458
Others
2.8
9.1
Comorbidities
Glucose tolerance (% yes)
Normal
36.1
12.1
0.022
Dysglycemic
63.9
87.9
0.022
Pancreatic insufficiency (% yes)
91.7
87.9
0.605
Hepatic dysfunction (% yes)
30.3
11.1
0.041
Home oxygen therapy (% yes)
5.6
15.2
0.190
Noninvasive ventilation (% yes)
2.8
6.1
0.507
ABPA (% yes)
16.7
27.3
0.290
BMI, body mass index; dysglycemic is presence of either glucose intolerance or diabetes; hepatic dysfunction is either abnormal level of hepatic enzymes or presence of cirrhosis; ABPA, allergic bronchopulmonary aspergillosis. Median and interval range are shown. value ≤ 0.05 represents Mann-Whitney Student’s t-test. Chi2 regression analysis.
