Research Article
Digital Clubbing Is Associated with Higher Serum KL-6 Levels and Lower Pulmonary Function in Patients with Interstitial Lung Disease
Table 3
Clinical data analysis between patients with and without clubbing.
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Note. Data are means ± standard error; SpO2 = pulse oximeter oxygen saturation; PaO2 = partial pressure of oxygen in arterial blood; PaCO2 = partial pressure of carbon dioxide in arterial blood; ILD = interstitial lung disease; KL-6 = Krebs von den Lugen-6; FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity; VC = vital capacity; DLCO = diffusing capacity of carbon monoxide; NSIP = nonspecific interstitial pneumonia; CTD-ILD = connective tissue disease-associated interstitial lung disease; †data were missing for eight patients in the clubbing (−) group for SpO2; 62 patients in the clubbing (−) group and 11 patients in the clubbing (−) group for PaO2 and PaCO2, respectively; three patients in the clubbing (−) group and one patient in the clubbing (+) group for KL-6; 22 patients in the clubbing (−) group and two patients in the clubbing (+) group for %FEV1, %FVC, and %VC; 28 patients in the clubbing (−) group and five patients in the clubbing (+) group for %DLCO and ILD-GAP index; ‡data were missing for six patients in the clubbing (−) group for SpO2; one patient in the clubbing (−) group for KL-6; nine patients in the clubbing (−) group for %FEV1, %FVC, and %VC; and 11 patients in the clubbing (−) group for %DLCO and ILD-GAP index; §data were missing for one patient in the clubbing (−) group for KL-6; four patients in the clubbing (−) group for %FEV1, %FVC, and %VC; and one patient in the clubbing (−) group for %DLCO and ILD-GAP index. |