Endobronchial Ultrasound Transbronchial Needle Aspiration in Thoracic Diseases: Much More than Mediastinal Staging

Table 4

Diagnostic performance of EBUS in the different groups.

EBUS	Overall	Group 1	Group 2	Group 3	Group 4	Group 5
Total	1891	728	401	320	290	152
True negative	441	193	6	97	25	120
False negative	121	50	6	17	24	24
True positive	1329	485	389	206	241	8
Performance	% (95% CI)	% (95% CI)	% (95% CI)	% (95% CI)	% (95% CI)	% (95% CI)
Sensitivity	91.7 (90.1–93.0)	90.7 (87.9–92.8)	98.5 (96.7–99.3)	92.4 (88.1–95.2)	90.9 (86.9–93.8)	25.0 (13.3–42.1)
Specificity	100 (99.1–100)	100 (98.0–100)	100 (61.0–100)	100 (96.2–100)	100 (86.7–100)	100 (96.9–100)
PPV	100 (99.7–100)	100 (99.2–100)	100 (99.0–100.)	100 (98.2–100)	100 (98.4–100)	100 (67.6–100)
NPV	78.5 (74.9–81.7)	79.4 (73.9–84.0)	50.0 (25.4–74.6)	85.1 (77.4–90.5)	51.0 (37.5–64.4)	83.3 (76.4–88.5)
Accuracy	93.6 (92.4–94.6)	93.1 (91.1–94.8)	98.5 (96.8–99.3)	94.7 (91.7–96.7)	91.7 (88.0–94.4)	84.2 (77.6–89.2)