Canadian Respiratory Journal / 2018 / Article / Tab 2

Review Article

Effects of Comorbidities on Asthma Hospitalization and Mortality Rates: A Systematic Review

Table 2

Study characteristics.

Author (year)Research typePopulationStudy length (years)CMDODMOSA
TotalControl (asthma-only)Comorbid condition

Kendzerska et al. [8]Retrospective cohort10M
Baarnes et al. [9]Retrospective cohort57,0531,8456624M
Yamauchi et al. [10]Retrospective cohort30,40519,8656,2793M and ER
Harada et al. [11]Retrospective65047417612M
Becerra et al. [12]Inpatient sample study179, 789136,1188,1893LOS
Vuillermin et al. [13]Cross-sectional analysis6154102051ER
Ahmedani et al. [14]Prospective follow-up study568N/A1871ER
Wiesenthal et al. [15]Prospective follow-up study4602272333ER
Hsiao et al. [16]Retrospective cohort17,7257663,54513ER

Description of results from each selected article regarding the significant differences in hospital/emergency room (ER) visits, mortality (M), and hospital length of stay (LOS) in patient due to the chronic disease comorbidity compared to the asthma-only control. C,  COPD/asthma comorbidity; MD,  mental disorder/asthma comorbidity; O,  obesity/asthma comorbidity; D ,  diabetes mellitus/asthma comorbidity; OSA ,  obstructive sleep apnea. This paper utilized a population health administrative data for all individuals living in Ontario, Canada (population of approximately 13 million in 2010) that are over the age of 35. No articles were found that discussed the clinical impacts of either hypertension-asthma, myocardial ischemia-asthma, or rhinitis/sinusitis-asthma comorbidity.

We are committed to sharing findings related to COVID-19 as quickly and safely as possible. Any author submitting a COVID-19 paper should notify us at to ensure their research is fast-tracked and made available on a preprint server as soon as possible. We will be providing unlimited waivers of publication charges for accepted articles related to COVID-19. Sign up here as a reviewer to help fast-track new submissions.