The Serum Level of IL-1B Correlates with the Activity of Chronic Pulmonary Aspergillosis

Figure 2

The comparison of IL-1B levels before and after surgery: (a) each dot represents an individual CPA patient. There was a clear upward trend of IL-1B level with the increase of lesion size before the surgery (solid line) and one month later after the surgery; almost all patients’ serum IL-1 decreased (61.3 ± 42.7 ng/L vs 23.7 ± 9.4 ng/L, ) (dotted line), especially in patients whose baseline IL-1 levels were over 20 ng/L. (b) The CT scan of a 63-year-old male CPA patient with multiple cavities, pleural thickening, aspergilloma, and consolidation in the left upper lobe. His serum IL-1 was 180 ng/L prior to the surgery. (c) 3 months later after he received a left upper lobectomy, no CPA lesions were seen in his chest CT and his serum IL-1 decreased to 23 ng/L.