The Serum Level of IL-1B Correlates with the Activity of Chronic Pulmonary Aspergillosis

Table 2

Multiple linear regression model for predicting serum IL-1B using age, gender, BMI, smoking status, TB, NTM infection, lung abscess, other acute respiratory infections, cancer, COPD, AIP, sarcoidosis, other interstitial diseases, diabetes mellitus, hypertension, cardiac disease, cerebrovascular disease, systemic CS or IS therapy, and pulmonary surgery history as covariates in all the subjects with chronic pulmonary aspergillosis.

Comorbid conditions		β Coefficient	Standard error	value
TB	None (reference)	—	—	—
	Treated	0.003	0.106	0.978
	Active/being treated	0.475	0.138	0.001
NTM infection		0.538	0.196	0.006
Lung abscess		0.975	0.304	0.001
Other acute respiratory infection		0.547	0.151	0.000
Cancer		0.542	0.147	0.000
COPD	None (reference)	—	—	—
	Stable	0.119	0.102	0.247
	Acute	0.612	0.164	0.000
AIP		0.818	0.305	0.008
Sarcoidosis		0.407	0.185	0.028
Systemic CS or IS therapy		−0.297	0.144	0.039

AIP: acute interstitial pneumonia; COPD: chronic obstructive pulmonary disease; CS: corticosteroid; ILD: interstitial lung disease; IS: immunosuppressive; NTM: nontuberculous mycobacterium.