Overexpression of MALAT1 Relates to Lung Injury through Sponging miR-425 and Promoting Cell Apoptosis during ARDS

Figure 1

MALAT1 level increased in ARDS patients’ plasma and PBMCs, and negatively correlates with miR-425 level in exosomes. (a) Total RNAs were extracted from plasma, plasmal exosomes, and PBMCs from ARDS patients and healthy controls, and the MALAT1 level was quantified by qRT-PCR. (b) Total RNAs were extracted from plasmal exosome and candidate miRNA level was detected by qRT-PCR. Results were shown as box-whisker diagram and data out of 95% CI were shown as dots. (c) Correlation between PBMCs MALAT1 level and exosomal miR-425 level.

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