Canadian Respiratory Journal

Research Article

Explorating the Involvement of Plasma Sestrin2 in Obstructive Sleep Apnea

Table 5

Demographic characteristics, sleep profiles, and blood measurements of the OSA patients changeing between pre-nCPAP and post-nCPAP.


	Pre-nCPAP (n = 14)	Post-nCPAP (n = 14)	value

Titration pressure (cm H₂O)	9.71 ± 1.69	—	—
Sestrin2 (ng/mL)	5.21 ± 2.32	4.01 ± 1.54	0.004
Age (years)	41.7 ± 7.25	—	—
BMI (kg/m²)	28.74 ± 4.80	28.71 ± 4.80	0.347
Waist-to-hip	0.93 ± 0.09	0.92 ± 0.09	0.131
TG (mmol/L)	1.78 ± 1.15	1.75 ± 1.11	0.286
TC (mmol/L)	4.26 ± 0.79	4.28 ± 0.79	0.727
LDL (mmol/L)	2.55 ± 0.60	2.48 ± 0.65	0.208
HDL (mmol/L)	0.95 ± 0.18	0.97 ± 0.32	0.629
FBG (mmol/L)	4.67 ± 0.60	4.62 ± 0.52	0.272
ESS (scores)	13.50 ± 4.87	6.93 ± 1.21	<0.001

Values are indicated as mean ± standard deviation. OSA, obstructive sleep apnea; nCPAP, nasal continuous positive airway pressure; BMI, body mass index; TG, triglycerides; TC, total cholesterol; LDL, low-density lipoprotein; HDL, high-density lipoprotein; FBG, fasting blood glucose; ESS, Epworth Sleepiness Score. , the results are statistically significant.