CXCL16 Induces the Progression of Pulmonary Fibrosis through Promoting the Phosphorylation of STAT3

Figure 2

The PF model was successfully constructed in mice. (a) The lung tissues of normal and model mice were stained by hematoxylin and eosin (H&E) and Masson, respectively, 200x. (b) The production of HYP was increased in lung tissues of PF model mice ( vs Normal). (c) The mRNA level of CXCR6, CTGF, and α-SMA was upregulated in lung tissues of PF model mice ( vs Normal). (d) The protein level of CXCR6, CTGF, α-SMA, STAT3, and p-STAT3 was promoted in lung tissues of PF model mice ( vs Normal).

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