Research Article

Lung Function and Relevant Clinical Factors in Very Low Birth Weight Preterm Infants with Chronic Lung Disease: An Observational Study

Table 2

Comparison of pulmonary function parameters between groups.

CLD (n = 27)No CLD (n = 18) value

Postnatal age on checking lung function (days old)93.30 ± 20.1455.39 ± 20.16<0.001
PMA on checking lung function (weeks)41.33 ± 2.2137.86 ± 2.42<0.001
Body weight on checking lung function (kg)2.73 ± 0.542.47 ± 0.610.010
Body length on checking lung function (cm)47.06 ± 3.7345.39 ± 4.000.121
z-score of body weight−2.39 ± 1.25−1.50 ± 1.250.018
z-score of body length−2.40 ± 1.69−1.48 ± 1.580.161
FRC (ml)59.84 ± 22.5456.24 ± 12.680.900
FRC (ml/kg)19.29 ± 12.1619.59 ± 11.210.757
FRC (ml/cm)1.28 ± 0.471.24 ± 0.240.828
TV (ml)23.68 ± 5.5323.70 ± 3.910.828
TV (ml/kg)8.86 ± 2.339.81 ± 1.400.050
MV (ml/kg)1334.83 ± 682.921067.36 ± 529.210.285
RR (min)78.31 ± 19.3578.08 ± 16.070.959
TI (s)0.38 ± 0.090.39 ± 0.090.667
TE (s)0.44 ± 0.160.43 ± 0.100.823
TI/Ttot0.63 ± 0.190.60 ± 0.200.361
TPTEF (s)0.18 ± 0.130.19 ± 0.060.081
TPTEF/TE (%)42.16 ± 18.2147.12 ± 15.930.285
LCI15.39 ± 4.2815.97 ± 3.680.761
M1/M04.56 ± 1.265.44 ± 2.680.455
M2/M039.75 ± 21.0543.95 ± 32.180.900

All continuous data are presented as mean ± SD. FRC: functional residual capacity; TV: tidal volume; TI: inspiratory time; TE: expiratory time; TPTEF: time to peak tidal expiratory flow; TPTEF/TE: the ratio of time to peak tidal expiratory flow over total expiratory time; M1/M0 and M2/M0: first and second moment ratios.